Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NOS3 | P29474 | 2/20 | 0.45 |
| ▸ | NOS1 | P29475 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1262317 | 0.83 | MAPT (0.48) | MAPTHPGDLMNARAB9AL3MBTL1 | |
| SCHEMBL17319344 | 0.83 | MAPT (0.48) | MAPTHPGDLMNARAB9AL3MBTL1 | |
| SCHEMBL16659380 | 0.82 | MAPT (0.52) | MAPTHPGDLMNARAB9AL3MBTL1 | |
| SCHEMBL21728512 | 0.81 | MAPT (0.46) | MAPTHPGDLMNARAB9AL3MBTL1 | |
| SCHEMBL50646 | 0.81 | MAPT (0.68) | MAPTHPGDLMNARAB9AL3MBTL1 | |
| SCHEMBL182327 | 0.80 | CYP2C9 (0.55) | MAPTHPGDLMNARAB9AL3MBTL1 | |
| SCHEMBL9683939 | 0.80 | MAPT (0.50) | MAPTHPGDLMNARAB9AL3MBTL1 | |
| SCHEMBL23036961 | 0.79 | LMNA (0.58) | MAPTHPGDLMNARAB9AL3MBTL1 | |
| SCHEMBL9790477 | 0.79 | MAPT (0.45) | MAPTHPGDLMNARAB9AL3MBTL1 | |
| SCHEMBL23036958 | 0.79 | LMNA (0.58) | MAPTHPGDLMNARAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250089-A | A kind of synthetic method of drug synthesis intermediate iodoacetamido choline | 成都东电艾尔科技有限公司 | 2018-07-06 | — | — | CN | claimed |
| CN-104016956-A | 5,2',4'-trihydroxyl-7-methyl-3-hydrocarbyl flavone analogue as well as preparation method and application thereof | UNIV GUANGXI TEACHERS EDUCATION | 2014-09-03 | — | — | CN | claimed |
| CN-108250089-A | A kind of synthetic method of drug synthesis intermediate iodoacetamido choline | 成都东电艾尔科技有限公司 | 2018-07-06 | — | — | CN | disclosed |
| CN-104016956-A | 5,2',4'-trihydroxyl-7-methyl-3-hydrocarbyl flavone analogue as well as preparation method and application thereof | UNIV GUANGXI TEACHERS EDUCATION | 2014-09-03 | — | — | CN | disclosed |
| WO-2012015901-A1 | METHODS FOR TREATING GASTRIC AND PANCREATIC MALIGNANCIES | GENZYME CORPORATION (US) | 2012-02-02 | — | — | WO | disclosed |
| US-20090118146-A1 | IMPREGNATING OIL COMPOSITION FOR SINTERED BEARING, BEARING APPARATUS AND SLIDING MEMBER | FUJIFILM CORPORATION (JP) | 2009-05-07 | — | — | US | disclosed |
| EP-1390337-A1 | PRECURSORS FOR KETONES AND ALDEHYDES | Givaudan SA (CH) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002096850-A1 | PRECURSORS FOR KETONES AND ALDEHYDES | GIVAUDAN SA (CH) | 2002-12-05 | — | — | WO | disclosed |
| EP-1054887-A1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | Amgen Inc. (US) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999040091-A1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC. (US) | 1999-08-12 | — | — | WO | disclosed |
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |