SCHEMBL5276589

SCHEMBL5276589

CCCCCc1nnnn1C(=O)n1cnnn1

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DAGLA Q9Y4D2 4/20 0.40
TRPV1 Q8NER1 1/20 0.31
ATM Q13315 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
FAAH O00519 1/20 0.31
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5274444 0.96 DAGLA (0.40) DAGLATRPV1FAAH
SCHEMBL5279769 0.90 DAGLA (0.38) DAGLATRPV1FAAH
SCHEMBL5276277 0.78 DAGLA (0.35) DAGLATRPV1FAAH
Bromide SCHEMBL27698944 0.75 DAGLA (0.46) DAGLATRPV1ATMSMN1; SMN2FAAH
SCHEMBL5275474 0.75 KCNJ1 (0.36) LMNATSHR
SCHEMBL5274003 0.73 TRPV1 (0.53) DAGLATRPV1FAAH
SCHEMBL5282490 0.70 KCNJ1 (0.31) FAAH
SCHEMBL5277887 0.67 THRB (0.32)
SCHEMBL5280089 0.66
SCHEMBL11802408 0.65 KDM4C (0.48) ATMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859783-A1 Brightening and/or colouring agent comprising N, N'-carbonyldiazoles and/or analagogues thereof Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed