SCHEMBL5279769

SCHEMBL5279769

CCCc1nnnn1C(=O)n1cnnn1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DAGLA Q9Y4D2 2/20 0.38
TRPV1 Q8NER1 2/20 0.33
FAAH O00519 2/20 0.33
HMOX1 P09601 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MGLL Q99685 1/20 0.31
KCNJ1 P48048 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5274444 0.92 DAGLA (0.40) DAGLATRPV1FAAHHMOX1ALDH1A1
SCHEMBL5276589 0.90 DAGLA (0.40) DAGLATRPV1FAAH
SCHEMBL5273653 0.89 DAGLA (0.39) DAGLATRPV1
SCHEMBL5277314 0.88 DAGLA (0.34) DAGLATRPV1FAAHHMOX1ALDH1A1
SCHEMBL5276277 0.81 DAGLA (0.35) DAGLATRPV1FAAHALDH1A1MGLL
SCHEMBL5275474 0.78 KCNJ1 (0.36) ALDH1A1KCNJ1
SCHEMBL5274003 0.76 TRPV1 (0.53) DAGLATRPV1FAAHHMOX1ALDH1A1
SCHEMBL28704644 0.74 DAGLA (0.45) DAGLATRPV1FAAHALDH1A1MGLL
SCHEMBL5280320 0.73 KCNJ1 (0.30) KCNJ1
SCHEMBL5275093 0.73 HMGCR (0.31) KCNJ1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859783-A1 Brightening and/or colouring agent comprising N, N'-carbonyldiazoles and/or analagogues thereof Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed