Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL527655 | 1.00 | ACP3 (0.42) | ACP3CNR2SMN1; SMN2HPGDP2RX7 | |
| SCHEMBL2346776 | 0.85 | ACP3 (0.46) | ACP3CNR2SMN1; SMN2HPGDMAOB | |
| SCHEMBL2351342 | 0.85 | ACP3 (0.46) | ACP3CNR2SMN1; SMN2HPGDMAOB | |
| SCHEMBL2703078 | 0.85 | ACP3 (0.46) | ACP3CNR2SMN1; SMN2HPGDMAOB | |
| SCHEMBL8887298 | 0.84 | ACP3 (0.42) | ACP3CNR2SMN1; SMN2HPGDMAOB | |
| Hydrochloric Acid SCHEMBL5595953 | 0.84 | ACP3 (0.45) | ACP3CNR2SMN1; SMN2HPGDMAOB | |
| SCHEMBL11556739 | 0.82 | FABP4 (0.38) | SMN1; SMN2LMNAGAATSHRMAPT | |
| SCHEMBL28969367 | 0.78 | ACP3 (0.45) | ACP3CNR2SMN1; SMN2P2RX7LMNA | |
| SCHEMBL5918008 | 0.76 | FABP4 (0.44) | ACP3LMNAKMT2A | |
| SCHEMBL28327500 | 0.76 | ACP3 (0.46) | ACP3CNR2P2RX7MAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111747881-B | Two isopentenyl substituted indole alkaloids with alpha-glucosidase inhibition effect, and preparation method and application thereof | 济南大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-111321095-B | Butenolide dimer with alpha-glucosidase inhibition effect and application thereof | 济南大学 | 2021-11-30 | — | — | CN | disclosed |
| CN-111747881-A | Two isopentenyl substituted indole alkaloids with alpha-glucosidase inhibition effect, and preparation method and application thereof | 济南大学 | 2020-10-09 | — | — | CN | disclosed |
| US-10793581-B2 | Stereochemically defined polypropionates and methods for making and using the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2020-10-06 | — | — | US | disclosed |
| CN-111334438-A | Preparation method of aromatic butenolide dimer and application of aromatic butenolide dimer in preparation of antibacterial drugs | 济南大学 | 2020-06-26 | — | — | CN | disclosed |
| CN-111321095-A | Butenolide dimer with α -glucosidase inhibition effect and application thereof | 济南大学 | 2020-06-23 | — | — | CN | disclosed |
| CN-111235042-A | Butenolide dimer with COX-2 inhibition and antioxidation effects and application thereof | 济南大学 | 2020-06-05 | — | — | CN | disclosed |
| US-20200055866-A1 | STEREOCHEMICALLY DEFINED POLYPROPIONATES AND METHODS FOR MAKING AND USING THE SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2020-02-20 | — | — | US | disclosed |
| US-10407439-B2 | Stereochemically defined polypropionates and methods for making and using the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2019-09-10 | — | — | US | disclosed |
| US-10160768-B2 | Stereochemically defined polypropionates and methods for making and using the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2018-12-25 | — | — | US | disclosed |
| EP-0524781-A1 | Therapeutic amides | ZENECA LIMITED (GB) | 1993-01-27 | — | — | EP | disclosed |
| US-5106750-A | Enzymatic resolution of hydroxycyclopentenones using lipase | G. D. SEARLE & CO. (US) | 1992-04-21 | — | — | US | disclosed |
| US-5064761-A | PROCESS FOR THE MANUFACTURE OF 4-ACYLAMINO-3-HYDROXYBUTYRIC ACID ESTERS | CIBA-GEIGY CORPORATION (US) | 1991-11-12 | — | — | US | disclosed |
| US-5010189-A | Processes for the preparation of 5-amino-4-hydroxy-valeric acid derivatives | CIBA-GEIGY CORPORATION (US) | 1991-04-23 | — | — | US | disclosed |
| US-4927507-A | Novel process for the manufacture of 4-acyloxy-3-hydroxyethyl-azetidinones | CIBA-GEIGY CORPORATION (US) | 1990-05-22 | — | — | US | disclosed |
| EP-0357009-A2 | Method of resolution of hydroxy-cyclopentenones using a lipase and transacylation agents | G.D. Searle & Co. (US) | 1990-03-07 | — | — | EP | disclosed |
| US-4898977-A | Processes for the preparation of 5-amino-4-hydroxyvaleric acid derivatives | CIBA-GEIGY CORPORATION (US) | 1990-02-06 | — | — | US | disclosed |
| EP-0319471-A2 | Resolution process | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |
| WO-1986004897-A1 | IMPROVEMENTS IN OR RELATING TO PHEROMONES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-08-28 | — | — | WO | disclosed |
| EP-0050351-A1 | Optically active or racemic alpha-hydroxyaldehydes and benzyl derivatives thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-04-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10407439-B2 | Stereochemically defined polypropionates and methods for making and using the same | FDPS, DHPS, ADCYAP1R1 | ACP3 39/4885CNR2 3265/4885SMN1; SMN2 4535/4885 |
| US-20200055866-A1 | STEREOCHEMICALLY DEFINED POLYPROPIONATES AND METHODS FOR MAKING AND USING THE SAME | FDPS, DHPS, ADCYAP1R1 | ACP3 39/4885CNR2 3265/4885SMN1; SMN2 4535/4885 |
| US-10793581-B2 | Stereochemically defined polypropionates and methods for making and using the same | FDPS, DHPS, ADCYAP1R1 | ACP3 39/4885CNR2 3265/4885SMN1; SMN2 4535/4885 |
| US-10160768-B2 | Stereochemically defined polypropionates and methods for making and using the same | FDPS, DHPS, ADCYAP1R1 | ACP3 39/4885CNR2 3265/4885SMN1; SMN2 4535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.