SCHEMBL527670

SCHEMBL527670

c1ccc(Cc2ncco2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.44
RAB9A P51151 4/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
NPC1 O15118 3/20 0.44
ALDH1A1 P00352 2/20 0.44
HPGD P15428 2/20 0.43
TSHR P16473 1/20 0.43
GPR55 Q9Y2T6 1/20 0.43
TAAR1 Q96RJ0 1/20 0.41
S1PR1 P21453 1/20 0.41
EDNRB P24530 1/20 0.41
EDNRA P25101 1/20 0.41
CES1 P23141 2/20 0.41
FAAH O00519 1/20 0.41
NCEH1 Q6PIU2 1/20 0.41
ADORA2A P29274 1/20 0.40
ADORA1 P30542 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 1/20 0.40
ELANE P08246 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL28708802 0.94 RAB9A (0.47) CALM1RAB9ASMN1; SMN2NPC1ALDH1A1
SCHEMBL6165634 0.83 S1PR1 (0.41) RAB9ASMN1; SMN2NPC1ALDH1A1S1PR1
SCHEMBL344823 0.82 CES1 (0.46) RAB9ASMN1; SMN2NPC1ALDH1A1HPGD
SCHEMBL6165832 0.81 CYP11B1 (0.45) LTA4H
SCHEMBL10687520 0.80 ESR1 (0.48) EDNRBEDNRA
SCHEMBL20773482 0.80 NPC1 (0.41) RAB9ASMN1; SMN2NPC1HPGDTAAR1
SCHEMBL6643942 0.80 EPHX2 (0.42) RAB9ASMN1; SMN2NPC1TAAR1EDNRB
SCHEMBL20773616 0.80 NPC1 (0.44) RAB9ASMN1; SMN2NPC1ALDH1A1HPGD
SCHEMBL15660842 0.80 CYP3A4 (0.48) RAB9ASMN1; SMN2NPC1ALDH1A1TSHR
SCHEMBL7704422 0.79 CYP1B1 (0.32) EDNRBEDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 523 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230422617-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD (CN) 2023-12-28 US claimed
EP-4291000-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS Kunshan Go-Visionox Opto-Electronics Co., Ltd. (CN) 2023-12-13 EP claimed
CN-113200969-B PI3K alpha selective inhibitor and preparation method and application thereof 中国药科大学 2022-11-25 CN claimed
EP-2652810-B9 METHOD OF FORMING A RADIATION-EMITTING ORGANIC-ELECTRONIC DEVICE OSRAM OLED GMBH (DE) 2021-11-10 EP claimed
EP-2652810-B1 METHOD OF FORMING A RADIATION-EMITTING ORGANIC-ELECTRONIC DEVICE OSRAM OLED GMBH (DE) 2021-08-11 EP claimed
US-20210011381-A1 NEGATIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, ELEMENT AND DISPLAY APPARATUS THAT INCLUDE CURED FILM, PRODUCTION METHOD FOR THE SAME TORAY INDUSTRIES, INC. (JP) 2021-01-14 US claimed
US-10802401-B2 Negative-type photosensitive resin composition, cured film, element and display apparatus that include cured film, production method for the same TORAY INDUSTRIES, INC. (JP) 2020-10-13 US claimed
EP-2807171-B1 HETEROCYCLIC COMPOUNDS AND METHODS FOR THEIR USE NOVARTIS AG (CH) 2020-08-12 EP claimed
US-10336707-B2 Heterocyclic derivatives modulating activity of certain protein kinases EUDENDRON S.R.L. (IT) 2019-07-02 US claimed
EP-3286371-B1 STRUCTURE WITH BREATHABLE FABRIC FOR THE PRODUCTION OF BALLISTIC AND STAB-RESISTANT PROTECTIONS SPA FRATELLI CITTERIO (IT) 2019-05-08 EP claimed
EP-1349856-B1 ISOINDOLIN-1-ONE GLUCOKINASE ACTIVATORS HOFFMANN LA ROCHE (CH) 2005-06-15 EP claimed
EP-0686691-B1 Aqueous emulsions with brighteners PROCTER & GAMBLE (US) 2001-08-08 EP claimed
EP-1090013-A1 PROPENYL CEPHALOSPORIN DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2001-04-11 EP claimed
WO-1999067255-A1 PROPENYL CEPHALOSPORIN DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 1999-12-29 WO claimed
WO-1995034621-A1 AQUEOUS EMULSIONS CONTAINING A HYDROPHOBIC BRIGHTENER, A HYDROPHILIC SURFACTANT AND A HYDROPHOBIC SURFACTANT THE PROCTER & GAMBLE COMPANY (US) 1995-12-21 WO claimed
EP-0686691-A1 Aqueous emulsions with brighteners THE PROCTER & GAMBLE COMPANY (US) 1995-12-13 EP claimed
EP-0140371-B1 INTERNAL LATENT IMAGE-TYPE DIRECT POSITIVE SILVER HALIDE LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1988-03-16 EP claimed
US-4629678-A A SULFUR COMPOUND AS A FINISH ADDITIVE: IMPROVED REVERSE PERFORMANCE; STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1986-12-16 US claimed
EP-0140371-A2 Internal latent image-type direct positive silver halide light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1985-05-08 EP claimed
US-3957517-A Dry stabilization of a silver halide photographic material FUJI PHOTO FILM CO., LTD. (JA) 1976-05-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10336707-B2 Heterocyclic derivatives modulating activity of certain protein kinases MAP4K2, MAP3K20, MAPKAPK2 CALM1 401/4885RAB9A 1372/4885SMN1; SMN2 1809/4885
US-20230422617-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS OCIAD1, OCIAD2, EML4 CALM1 1778/4885RAB9A 2180/4885SMN1; SMN2 2655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.