Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.72 |
| ▸ | HTR2C | P28335 | 3/20 | 0.72 |
| ▸ | DRD4 | P21917 | 1/20 | 0.72 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.72 |
| ▸ | HTR1D | P28221 | 1/20 | 0.72 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.72 |
| ▸ | HTR7 | P34969 | 1/20 | 0.72 |
| ▸ | HTR2B | P41595 | 1/20 | 0.72 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.72 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27498823 | 0.99 | HTR2A (0.70) | HTR2AHTR2CDRD4SLC6A2HTR1D | |
| SCHEMBL6110885 | 0.86 | HTR2A (0.74) | HTR2AHTR2CDRD4SLC6A2HTR1D | |
| SCHEMBL5274694 | 0.85 | HTR2A (0.73) | HTR2AHTR2CDRD4SLC6A2HTR1D | |
| SCHEMBL6110794 | 0.83 | HTR2A (0.70) | HTR2AHTR2CDRD4SLC6A2HTR1D | |
| Pruvanserin SCHEMBL29379046 | 0.83 | HTR2A (1.00) | HTR2AHTR2CDRD4SLC6A2HTR1D | |
| Pruvanserin SCHEMBL678751 | 0.83 | HTR2A (1.00) | HTR2AHTR2CDRD4SLC6A2HTR1D | |
| Pruvanserin SCHEMBL9104227 | 0.83 | HTR2A (1.00) | HTR2AHTR2CDRD4SLC6A2HTR1D | |
| SCHEMBL6109872 | 0.83 | HTR2A (0.69) | HTR2AHTR2CDRD4SLC6A2HTR1D | |
| Pruvanserin SCHEMBL678953 | 0.83 | HTR2A (0.98) | HTR2AHTR2CDRD4SLC6A2HTR1D | |
| Pruvanserin SCHEMBL29489913 | 0.83 | HTR2A (0.98) | HTR2AHTR2CDRD4SLC6A2HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914669-A1 | INKJET INK COMPOSITION | Domino Printing Sciences PLC (GB) | 2015-09-09 | — | — | EP | claimed |
| WO-2014068280-A1 | INKJET INK COMPOSITION | DOMINO PRINTING SCIENCES PLC (GB) | 2014-05-08 | — | — | WO | claimed |
| US-7084143-B2 | N-(indolecarbonyl) piperazine derivatives | MERCK PATENT GMBH (DE) | 2006-08-01 | — | — | US | claimed |
| US-6838461-B1 | N-(indolcarbonyl-)piperazine derivatives | MERCK PATENT GMBH (DE) | 2005-01-04 | — | — | US | claimed |
| US-20230086403-A1 | LAMINATE, HARD COATING FILM, AND COATING MATERIAL COMPOSITION | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2023-03-23 | — | — | US | disclosed |
| EP-4116085-A1 | LAMINATE, HARD-COAT COATING FILM, AND COATING MATERIAL COMPOSITION | Asahi Kasei Kabushiki Kaisha (JP) | 2023-01-11 | — | — | EP | disclosed |
| EP-2914669-B1 | INKJET INK COMPOSITION | DOMINO PRINTING SCIENCES PLC (GB) | 2018-12-05 | — | — | EP | disclosed |
| US-9670372-B2 | Inkjet ink composition | DOMINO PRINTING SCIENCES PLC (GB) | 2017-06-06 | — | — | US | disclosed |
| US-20150291816-A1 | INKJET INK COMPOSITION | DOMINO PRINTING SCIENCES PLC (GB) | 2015-10-15 | — | — | US | disclosed |
| EP-2914669-A1 | INKJET INK COMPOSITION | Domino Printing Sciences PLC (GB) | 2015-09-09 | — | — | EP | disclosed |
| WO-2014068280-A1 | INKJET INK COMPOSITION | DOMINO PRINTING SCIENCES PLC (GB) | 2014-05-08 | — | — | WO | disclosed |
| CN-101684174-A | Amphiphilic biologically degradable polyester comb-grafted copolymer and temperature-sensitive situ-gel system thereof | UNIV TIANJIN | 2010-03-31 | — | — | CN | disclosed |
| US-20050096330-A1 | N-(indolecarbonyl) piperazine derivatives | BOETTCHER HENNING (DE) | 2005-05-05 | — | — | US | disclosed |
| US-20050014766-A1 | Use of n-(indolecarbonyl-)piperazine derivatives | MERCK PATENT GMBH (DE) | 2005-01-20 | — | — | US | disclosed |
| US-6838461-B1 | N-(indolcarbonyl-)piperazine derivatives | MERCK PATENT GMBH (DE) | 2005-01-04 | — | — | US | disclosed |
| EP-1198453-B9 | N-(INDOLCARBONYL-)PIPERAZIN DERIVATIVES | MERCK PATENT GMBH (DE) | 2004-11-10 | — | — | EP | disclosed |
| WO-2004032932-A1 | USE OF 5-HT2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF SLEEP DISORDERS | MERCK PATENT GMBH (DE) | 2004-04-22 | — | — | WO | disclosed |
| US-20030078346-A1 | Polymer-bonded functional agents | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1198453-B1 | N-(INDOLCARBONYL-)PIPERAZIN DERIVATIVES | MERCK PATENT GMBH (DE) | 2003-04-09 | — | — | EP | disclosed |
| US-5100984-A | Acrylic and vinyl amide polymers, dispersants for construction materials | SIKA AG VORM. KASPAR WINKLER & CO. (CH) | 1992-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014766-A1 | Use of n-(indolecarbonyl-)piperazine derivatives | GPR119, CHRM1, HTR1A | HTR2A 11/4885HTR2C 5/4885DRD4 46/4885 |
| US-20050096330-A1 | N-(indolecarbonyl) piperazine derivatives | HTR2A, HTR2B, HTR2C | HTR2A 1/4885HTR2C 3/4885DRD4 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.