Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.54 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.54 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 11/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.47 |
| ▸ | GRIK3 | Q13003 | 5/20 | 0.47 |
| ▸ | GRIK5 | Q16478 | 5/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.47 |
| ▸ | GRM8 | O00222 | 2/20 | 0.47 |
| ▸ | GRM6 | O15303 | 2/20 | 0.47 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Asparagine SCHEMBL5639005 | 0.90 | GRIK1 (0.56) | EGLN1GRIK1GRIK2GRIA4GRIK3 | |
| Alpha-Ketoglutaric Acid SCHEMBL4366423 | 0.88 | MAPK1 (0.58) | MAPK1SLC13A3EGLN1OR51E2GRIK1 | |
| Alpha-Ketoglutaric Acid SCHEMBL1471943 | 0.88 | MAPK1 (0.58) | MAPK1SLC13A3EGLN1OR51E2GRIK1 | |
| Asparagine SCHEMBL28317631 | 0.88 | GRIK1 (0.54) | EGLN1GRIK1GRIK2GRIA4GRIK3 | |
| Glutamine SCHEMBL1033431 | 0.83 | ALOX15 (0.70) | MAPK1SLC13A3EGLN1OR51E2GRIK1 | |
| Glutamine SCHEMBL1033433 | 0.83 | ALOX15 (0.70) | MAPK1SLC13A3EGLN1OR51E2GRIK1 | |
| Asparagine SCHEMBL27669167 | 0.81 | GRIK1 (0.56) | GRIK1GRIK2GRIA4GRIK3GRIK5 | |
| Asparagine SCHEMBL8827 | 0.81 | — | — | |
| Asparagine SCHEMBL8826 | 0.81 | — | — | |
| Asparagine SCHEMBL288093 | 0.81 | ALOX15 (0.56) | GRIK1GRIK2GRIA4GRIK3GRIK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006016828-A2 | USE OF ALPHA KETOGLUTARATE FOR TREATING ALZHEIMER, PARKINSON | SGP & SONS AB (SE) | 2006-02-16 | — | — | WO | claimed |
| WO-2006016828-A8 | USE OF ALPHA KETOGLUTARATE FOR TREATING ALZHEIMER, PARKINSON | SGP & SONS AB (SE) | 2007-07-19 | — | — | WO | disclosed |
| WO-2006016828-A3 | USE OF ALPHA KETOGLUTARATE FOR TREATING ALZHEIMER, PARKINSON | SGP & SONS AB (SE) | 2006-06-08 | — | — | WO | disclosed |
| WO-2006016828-A2 | USE OF ALPHA KETOGLUTARATE FOR TREATING ALZHEIMER, PARKINSON | SGP & SONS AB (SE) | 2006-02-16 | — | — | WO | disclosed |
| WO-2006016828-A2 | USE OF ALPHA KETOGLUTARATE FOR TREATING ALZHEIMER, PARKINSON | SGP & SONS AB (SE) | 2006-02-16 | — | — | WO | disclosed |