Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22810947 | 0.92 | MAOB (0.41) | MAOBHSD11B1HRH3SLC9A1CACNA2D1 | |
| SCHEMBL5284084 | 0.87 | GABRB3 (0.41) | MAOBGABRB3GABRA2GABRB2MAOA | |
| SCHEMBL5275440 | 0.83 | MAOB (0.58) | MAOBHSD11B1MAOAHRH3SLC9A1 | |
| SCHEMBL5282328 | 0.82 | MAOB (0.53) | MAOBHSD11B1GABRB3GABRA2GABRB2 | |
| SCHEMBL5277268 | 0.82 | MAOB (0.49) | MAOBHSD11B1GABRB3MAOA | |
| SCHEMBL5273967 | 0.80 | MAOA (0.40) | MAOBHSD11B1GABRB3GABRA2GABRB2 | |
| SCHEMBL5278890 | 0.80 | SLC9A1 (0.42) | MAOBHSD11B1GABRB3MAOATSHR | |
| SCHEMBL5278588 | 0.78 | — | — | |
| SCHEMBL5274168 | 0.78 | MAOB (0.42) | MAOBHSD11B1 | |
| SCHEMBL5280096 | 0.78 | MAOB (0.42) | MAOBHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |