Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672977 | 0.98 | TSHR (0.46) | TSHRTDP1MAPTCACNA1BAPBA1 | |
| Malonic Acid SCHEMBL31256740 | 0.98 | TSHR (0.46) | TSHRTDP1MAPTCACNA1BAPBA1 | |
| SCHEMBL309469 | 0.98 | TSHR (0.46) | TSHRTDP1MAPTCACNA1BAPBA1 | |
| Butane SCHEMBL3817891 | 0.92 | TSHR (0.55) | TSHRTDP1MAPTCACNA1BAPBA1 | |
| SCHEMBL7690120 | 0.89 | TSHR (0.43) | TSHRTDP1MAPTCACNA1BAPBA1 | |
| SCHEMBL57069 | 0.87 | TSHR (0.52) | TSHRTDP1MAPTCACNA1BAPBA1 | |
| Acetoacetic Acid SCHEMBL1318189 | 0.86 | TSHR (0.44) | TSHRTDP1MAPTCACNA1BAPBA1 | |
| Lithium SCHEMBL31366079 | 0.85 | TSHR (0.50) | TSHRTDP1MAPTCACNA1BAPBA1 | |
| SCHEMBL8865453 | 0.85 | TSHR (0.50) | TSHRTDP1MAPTCACNA1BAPBA1 | |
| SCHEMBL8521347 | 0.85 | TDP1 (0.36) | TSHRTDP1MAPTCACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 920 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335358-B | Synthesis of Capsaicin Derivatives | 阿克西赫姆公司 | 2024-07-12 | — | — | CN | claimed |
| CN-114478229-B | Preparation method of azelaic acid | 武汉华尔生物科技有限公司 | 2024-07-12 | — | — | CN | claimed |
| EP-4352129-A1 | MICHAEL ADDITION CURABLE COMPOSITION, COATING COMPOSITION CONTAINING THE SAME, AND COATED ARTICLE | Guangdong Huarun Paints Co. Ltd. (CN) | 2024-04-17 | — | — | EP | claimed |
| US-11891351-B2 | Synthesis of capsaicin derivatives | AXICHEM AS (NO) | 2024-02-06 | — | — | US | claimed |
| CN-116375550-A | Method for resolving racemate compound by enantioselective reverse micelle extraction | 中南大学 | 2023-07-04 | — | — | CN | claimed |
| CN-115466532-B | Michael addition curable composition, coating composition comprising the same, and coated article | 广东华润涂料有限公司 | 2023-05-02 | — | — | CN | claimed |
| US-20230060251-A1 | SYNTHESIS OF CAPSAICIN DERIVATIVES | AXICHEM AS (NO) | 2023-03-02 | — | — | US | claimed |
| EP-4121408-A1 | SYNTHESIS OF CAPSAICIN DERIVATIVES | Axichem AB (NO) | 2023-01-25 | — | — | EP | claimed |
| US-20230002635-A1 | MICHAEL ADDITION CURABLE COMPOSITION, COATING COMPOSITION CONTAINING THE SAME, AND COATED ARTICLE | Sherwin-Williams (Guangdong) New Material Co., Ltd. (CN) | 2023-01-05 | — | — | US | claimed |
| WO-2022257689-A1 | MICHAEL ADDITION CURABLE COMPOSITION, COATING COMPOSITION CONTAINING THE SAME, AND COATED ARTICLE | GUANGDONG HUARUN PAINTS CO., LTD. (CN) | 2022-12-15 | — | — | WO | claimed |
| EP-0152319-B1 | PROCESS FOR OBTAINING COMPOUNDS WITH AN ALKOXYACYLIDENE GROUP | RHONE-POULENC CHIMIE (FR) | 1987-07-22 | — | — | EP | claimed |
| EP-0168305-B1 | PROCESS FOR THE STABILISATION OF ALKYL ALKOXYALKYLIDENE MALONATES | RHONE-POULENC CHIMIE (FR) | 1987-04-22 | — | — | EP | claimed |
| EP-0195053-A1 | PROCESS FOR PREPARING 1,3-CYCLOHEXANEDIONE DERIVATIVES AND INTERMEDIATES THEREFOR. | CHEVRON RES & TECH (US) | 1986-09-24 | — | — | EP | claimed |
| WO-1986002065-A1 | PROCESS FOR PREPARING 1,3-CYCLOHEXANEDIONE DERIVATIVES AND INTERMEDIATES THEREFOR | CHEVRON RESEARCH COMPANY (US) | 1986-04-10 | — | — | WO | claimed |
| US-4535137-A | Method for making a salt free solid polymer from a polymer emulsion | ROHM GMBH (DE) | 1985-08-13 | — | — | US | claimed |
| US-4495354-A | Process for bicyclic diketones | HOFFMANN-LA ROCHE INC. (US) | 1985-01-22 | — | — | US | claimed |
| EP-0040469-B1 | POLYURETHANE SEALANT SYSTEM AND METHOD OF FORMING A HIGH TENSILE STRENGTH SEAL ON GLASS AND/OR METAL | Products Research and Chemical Corporation (US) | 1984-07-25 | — | — | EP | claimed |
| EP-0049555-B1 | 2-TRIFLUOROMETHYL-4-HYDROXY-3 QUINOLINE-CARBOXYLIC-ACID DERIVATIVES AND THEIR PREPARATION | ROUSSEL-UCLAF (FR) | 1984-02-22 | — | — | EP | claimed |
| US-4343915-A | THERMOSET PROTECTIVE COATINGS | SCM CORPORATION (US) | 1982-08-10 | — | — | US | claimed |
| US-4284751-A | Polyurethane sealant system | PRODUCTS RESEARCH & CHEMICAL CORP. (US) | 1981-08-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11891351-B2 | Synthesis of capsaicin derivatives | TRPV1, TRPV6, HCAR3 | TSHR 4786/4885TDP1 4355/4885MAPT 3096/4885 |
| US-20230060251-A1 | SYNTHESIS OF CAPSAICIN DERIVATIVES | TRPV1, TRPV6, HCAR3 | TSHR 4786/4885TDP1 4355/4885MAPT 3096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.