SCHEMBL5278441

SCHEMBL5278441

CCCn1nnc(CC)c1C#N

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 1/20 0.36
ALDH1A1 P00352 1/20 0.33
GRM2 Q14416 1/20 0.33
TOP2A P11388 1/20 0.31
CYP17A1 P05093 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5280521 0.89 SLC9A1 (0.39) SLC9A1GRM2TOP2A
SCHEMBL5276840 0.87 SLC9A1 (0.35) SLC9A1ALDH1A1GRM2TOP2A
SCHEMBL5274744 0.86 SLC9A1 (0.42) SLC9A1ALDH1A1GRM2
SCHEMBL5281690 0.85 MAOA (0.34) SLC9A1
SCHEMBL5285349 0.84 ALDH1A1 (0.36) SLC9A1ALDH1A1GRM2CYP17A1
SCHEMBL5278277 0.83 SLC9A1 (0.33) SLC9A1
SCHEMBL5275820 0.83 HTT (0.33) SLC9A1ALDH1A1
SCHEMBL5279348 0.79 SLC9A1 (0.37) SLC9A1ALDH1A1GRM2TOP2ACYP17A1
SCHEMBL5280296 0.79 SLC9A1 (0.37) SLC9A1ALDH1A1GRM2TOP2ACYP17A1
SCHEMBL5275441 0.79 GLA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859781-A2 Brightening and/or colouring agent with triazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed