Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | LIPE | Q05469 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5111572 | 0.87 | TDP1 (0.51) | L3MBTL1LMNAMAPTGPBAR1SCN9A | |
| SCHEMBL5282850 | 0.85 | L3MBTL1 (0.57) | L3MBTL1LMNAMAPTGPBAR1TDP1 | |
| SCHEMBL5282827 | 0.84 | KMT2A (0.45) | L3MBTL1LMNAMAPTALKSCN9A | |
| SCHEMBL5289303 | 0.81 | L3MBTL1 (0.45) | L3MBTL1LMNAGPBAR1SCN9ACYP1A2 | |
| SCHEMBL5126291 | 0.81 | CYP1A2 (0.56) | L3MBTL1LMNAMAPTTDP1CYP1A2 | |
| SCHEMBL5280143 | 0.75 | L3MBTL1 (0.61) | L3MBTL1LMNAMAPTSCN9ATDP1 | |
| SCHEMBL5119039 | 0.75 | TDP1 (0.52) | L3MBTL1LMNAMAPTTDP1CYP1A2 | |
| SCHEMBL5296867 | 0.74 | CYP1A2 (0.50) | L3MBTL1LMNAMAPTALKSCN9A | |
| SCHEMBL5282184 | 0.74 | L3MBTL1 (0.50) | L3MBTL1LMNAMAPTTDP1CYP1A2 | |
| SCHEMBL5285421 | 0.73 | LMNA (0.41) | L3MBTL1LMNAMAPTALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866289-A1 | PYRIMIDINE CARBOXYLIC ACID DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006097220-A1 | PYRIMIDINE CARBOXYLIC ACID DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-09-21 | — | — | WO | disclosed |