Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5276547 | 0.85 | ALDH1A1 (0.32) | CYP2C19CYP1A2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL5277172 | 0.79 | CYP2C19 (0.32) | CYP2C19CYP1A2ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL5274943 | 0.79 | CYP1A2 (0.34) | CYP2C19CYP1A2ALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL5275854 | 0.79 | ALDH1A1 (0.31) | CYP2C19CYP1A2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL5279635 | 0.79 | KDM4E (0.41) | CYP2C19CYP1A2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL5283254 | 0.77 | ALDH1A1 (0.32) | CYP2C19CYP1A2ALDH1A1SMN1; SMN2TOP2A | |
| SCHEMBL5278565 | 0.77 | MAPT (0.32) | MAPT | |
| SCHEMBL5281991 | 0.77 | LMNA (0.34) | CYP2C19CYP1A2ALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL5278672 | 0.75 | DPP4 (0.32) | — | |
| SCHEMBL5278586 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |