Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5276495 | 0.87 | SMN1; SMN2 (0.36) | LMNAMAPTHTTBLMKMT2A | |
| SCHEMBL5283309 | 0.85 | LMNA (0.30) | LMNAMAPTHTTBLMKMT2A | |
| SCHEMBL5276599 | 0.84 | LMNA (0.32) | LMNAMAPTHTTBLMKMT2A | |
| SCHEMBL5275597 | 0.82 | — | — | |
| SCHEMBL5280108 | 0.77 | CYP2C19 (0.32) | LMNAMAPTHTTBLMKMT2A | |
| SCHEMBL5278304 | 0.77 | ALDH1A1 (0.38) | LMNAMAPTHTTBLMKMT2A | |
| SCHEMBL5276547 | 0.77 | ALDH1A1 (0.32) | LMNAMAPTHTTBLMKMT2A | |
| SCHEMBL5277744 | 0.75 | GRIA1 (0.34) | LMNAMAPTHTTBLMKMT2A | |
| SCHEMBL5279635 | 0.75 | KDM4E (0.41) | LMNAMAPTHTTCYP2C19CYP1A2 | |
| SCHEMBL5277172 | 0.75 | CYP2C19 (0.32) | LMNAMAPTCYP3A4CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |