Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 19/20 | 0.50 |
| ▸ | BCHE | P06276 | 18/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10286184 | 0.80 | BRD4 (0.44) | ACHEBCHECYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL527692 | 0.77 | BRD4 (0.47) | ACHEBCHECYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL26330071 | 0.77 | ACHE (0.50) | ACHEBCHEGRIN1GRIN2AGRIN2B | |
| SCHEMBL527120 | 0.75 | ACHE (0.46) | ACHEBCHECYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL24287266 | 0.75 | LMNA (0.57) | ACHEBCHEGRIN1GRIN2AGRIN2B | |
| SCHEMBL526243 | 0.73 | KDM4E (0.45) | ACHEBCHEGRIN1GRIN2AGRIN2B | |
| SCHEMBL28623444 | 0.72 | SYK (0.51) | ACHEBCHECYP1A2 | |
| SCHEMBL15127494 | 0.72 | KDM4E (0.44) | ACHEBCHEGRIN1GRIN2ASMN1; SMN2 | |
| SCHEMBL24287389 | 0.72 | LMNA (0.57) | ACHEBCHECYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL527227 | 0.70 | NOS3 (0.64) | ACHEBCHEGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598487-A1 | NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES | Syngenta Participations AG (CH) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012013754-A1 | NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-02-02 | — | — | WO | disclosed |