Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBTPS1 | Q14703 | 4/20 | 0.45 |
| ▸ | AGER | Q15109 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12467970 | 0.79 | AGER (0.47) | AGERMTNR1ADCUN1D1SLC6A2SLC6A4 | |
| SCHEMBL3811903 | 0.76 | DCUN1D1 (0.58) | AGERMTNR1ADCUN1D1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL21410210 | 0.75 | DCUN1D1 (0.57) | AGERMTNR1ADCUN1D1SLC6A2SLC6A4 | |
| SCHEMBL619150 | 0.74 | SLC6A2 (0.71) | AGERMTNR1ADCUN1D1SLC6A2SLC6A4 | |
| SCHEMBL15521608 | 0.73 | DCUN1D1 (0.60) | AGERMTNR1ADCUN1D1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL22797899 | 0.72 | SLC6A2 (0.70) | AGERMTNR1ADCUN1D1SLC6A2SLC6A4 | |
| SCHEMBL526963 | 0.72 | AGER (0.46) | AGERMTNR1ADCUN1D1SLC6A2SLC6A4 | |
| SCHEMBL6622412 | 0.71 | DCUN1D1 (0.54) | AGERMTNR1ADCUN1D1SLC6A2SLC6A4 | |
| SCHEMBL6633233 | 0.70 | DCUN1D1 (0.60) | AGERMTNR1ADCUN1D1SLC6A2SLC6A4 | |
| SCHEMBL27787053 | 0.70 | SLC6A4 (0.61) | DCUN1D1SLC6A2SLC6A4SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598483-A1 | AMPK-ACTIVATING HETEROCYCLIC COMPOUNDS AND METHODS FOR USING THE SAME | Rigel Pharmaceuticals, Inc. (US) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012016217-A1 | AMPK-ACTIVATING HETEROCYCLIC COMPOUNDS AND METHODS FOR USING THE SAME | RIGEL PHARMACEUTICALS, INC. (US) | 2012-02-02 | — | — | WO | disclosed |