SCHEMBL5283248

SCHEMBL5283248

CCCCn1cnnc1CC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
KMT2A Q03164 2/20 0.40
POLB P06746 1/20 0.40
LMNA P02545 1/20 0.39
TLR8 Q9NR97 3/20 0.38
ADORA2A P29274 3/20 0.37
TSHR P16473 2/20 0.35
CYP1A2 P05177 1/20 0.35
AMPD2 Q01433 1/20 0.34
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
CHRNA1 P02708 1/20 0.33
CHRNG P07510 1/20 0.33
CHRNB1 P11230 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
CHRND Q07001 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5280196 0.88 HSD11B1 (0.34) ALDH1A1ADORA2ACHRNB2CHRNA7CHRNA4
SCHEMBL5274280 0.86 ALDH1A1 (0.39) ALDH1A1KMT2APOLBLMNATLR8
SCHEMBL5278999 0.86 ALDH1A1 (0.39) ALDH1A1KMT2APOLBLMNATLR8
SCHEMBL5657308 0.85 AMPD2 (0.38) ALDH1A1KMT2APOLBLMNATLR8
Hydrochloric Acid SCHEMBL5654434 0.83 ALDH1A1 (0.37) ALDH1A1KMT2APOLBLMNATLR8
SCHEMBL5282719 0.82 ALDH1A1 (0.36) ALDH1A1KMT2APOLBLMNATLR8
SCHEMBL5278340 0.82 ALDH1A1 (0.36) ALDH1A1KMT2APOLBLMNATLR8
SCHEMBL1083103 0.81 TLR8 (0.40) ALDH1A1KMT2APOLBLMNATLR8
SCHEMBL28114461 0.79 TLR8 (0.39) ALDH1A1TLR8TSHRAMPD2SLC9A1
SCHEMBL5275734 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859781-A2 Brightening and/or colouring agent with triazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed