Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.49 |
| ▸ | BCHE | P06276 | 5/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5287676 | 0.94 | ACHE (0.57) | ACHEBCHEMTNR1AMTNR1BHTR1A | |
| SCHEMBL6038046 | 0.91 | ACHE (0.48) | ACHEBCHEMTNR1AMTNR1B | |
| SCHEMBL5278655 | 0.88 | BCHE (0.59) | ACHEBCHE | |
| SCHEMBL6037985 | 0.85 | BCHE (0.55) | ACHEBCHEMTNR1AMTNR1B | |
| SCHEMBL5279913 | 0.83 | BCHE (0.60) | ACHEBCHEHTR1ASLC6A4 | |
| SCHEMBL5281968 | 0.79 | SPR (0.54) | ACHEBCHEMTNR1AMTNR1BHTR1A | |
| SCHEMBL5282166 | 0.79 | ACHE (0.53) | ACHEBCHEHTR1A | |
| SCHEMBL5282667 | 0.77 | BCHE (0.55) | ACHEBCHE | |
| SCHEMBL5291489 | 0.76 | BCHE (0.52) | ACHEBCHE | |
| SCHEMBL5289480 | 0.75 | BCHE (0.56) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863804-A1 | INHIBITORS OF HISTONE DEACETYLASE | Methylgene, Inc. (CA) | 2007-12-12 | — | — | EP | claimed |
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | claimed |