Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.55 |
| ▸ | ACHE | P22303 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SPR | P35270 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6038046 | 0.94 | ACHE (0.48) | BCHEACHEMAPTMTNR1AMTNR1B | |
| SCHEMBL5281968 | 0.93 | SPR (0.54) | BCHEACHEMTNR1AMTNR1BSPR | |
| SCHEMBL5287676 | 0.91 | ACHE (0.57) | BCHEACHEMAPTMTNR1AMTNR1B | |
| SCHEMBL5282166 | 0.88 | ACHE (0.53) | BCHEACHEMAPTALDH1A1MEN1 | |
| SCHEMBL5280227 | 0.85 | ACHE (0.49) | BCHEACHEMTNR1AMTNR1B | |
| SCHEMBL5282667 | 0.84 | BCHE (0.55) | BCHEACHEMEN1KMT2A | |
| SCHEMBL5278902 | 0.79 | BCHE (0.47) | BCHEACHEMAPTALDH1A1MEN1 | |
| SCHEMBL5278655 | 0.79 | BCHE (0.59) | BCHEACHE | |
| SCHEMBL6038130 | 0.78 | HTR2A (0.69) | BCHEACHEMAPTMTNR1AMTNR1B | |
| SCHEMBL5291489 | 0.78 | BCHE (0.52) | BCHEACHEMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | claimed |
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | BCHE 1641/4885ACHE 3161/4885MAPT 3848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.