SCHEMBL5280276

SCHEMBL5280276

CC(Oc1ccccc1)Oc1ccc(C2=CCCCC2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.40
ACMSD Q8TDX5 2/20 0.39
HTR1A P08908 3/20 0.39
CYP1A2 P05177 1/20 0.38
GAA P10253 1/20 0.38
CYP2C9 P11712 1/20 0.38
PKM P14618 1/20 0.38
CYP2C19 P33261 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KCNH2 Q12809 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
PRMT5 O14744 1/20 0.36
WDR77 Q9BQA1 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
GPR88 Q9GZN0 2/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
CHRNB4 P30926 2/20 0.35
CHRNA3 P32297 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5280269 0.78 HRH3 (0.55) ACMSDPKMTDP1KCNH2HRH3
SCHEMBL8711734 0.76 LTA4H (0.46) ACMSDKCNH2HRH3NPC1RAB9A
SCHEMBL6345485 0.75 ACMSD (0.50) PTGS2ACMSDTDP1MEN1KMT2A
SCHEMBL8380044 0.75 ACMSD (0.49) PTGS2ACMSDTDP1MEN1KMT2A
SCHEMBL191429 0.75 ACMSD (0.49) PTGS2ACMSDTDP1MEN1KMT2A
SCHEMBL10489436 0.74 NPC1 (0.53) PTGS2ACMSDGAAKCNH2HRH3
SCHEMBL22382753 0.74 KCNH2 (0.45) PTGS2ACMSDTDP1KCNH2HRH3
SCHEMBL1094676 0.73 ACMSD (0.47) PTGS2ACMSDHTR1ATDP1MEN1
SCHEMBL1109740 0.73 ACMSD (0.47) PTGS2ACMSDHTR1ATDP1MEN1
SCHEMBL8360447 0.73 ACMSD (0.47) PTGS2ACMSDHTR1ATDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006138653-A9 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORP (US) 2007-03-01 WO disclosed
WO-2006138653-A1 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORPORATION (US) 2006-12-28 WO disclosed