Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | BAX | Q07812 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | GALR1 | P47211 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22382753 | 0.86 | KCNH2 (0.45) | KCNH2HRH3NPC1ACMSDRAB9A | |
| SCHEMBL6344544 | 0.81 | ACMSD (0.49) | KCNH2HRH3ACMSD | |
| SCHEMBL360448 | 0.81 | ACMSD (0.47) | KCNH2HRH3ACMSD | |
| SCHEMBL5280269 | 0.79 | HRH3 (0.55) | LTA4HKCNH2HRH3ACMSDMAOA | |
| SCHEMBL5280276 | 0.76 | PTGS2 (0.40) | LTA4HKCNH2HRH3NPC1ACMSD | |
| SCHEMBL8939884 | 0.76 | KCNH2 (0.47) | KCNH2HRH3NPC1ACMSDRAB9A | |
| SCHEMBL6345485 | 0.75 | ACMSD (0.50) | ACMSD | |
| SCHEMBL29140058 | 0.75 | ADRA2A (0.53) | LTA4HTSHRGSTP1NPC1NR1H2 | |
| SCHEMBL191429 | 0.74 | ACMSD (0.49) | ACMSD | |
| SCHEMBL8380044 | 0.74 | ACMSD (0.49) | ACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1077568-C | Phenoxyphenyl cyclopentenyl hydroxyureas | PFIZER (US) | 2002-01-09 | — | — | CN | disclosed |
| CN-1077568-C | Phenoxyphenyl cyclopentenyl hydroxyureas | PFIZER (US) | 2002-01-09 | — | — | CN | disclosed |
| US-5792882-A | Phenoxyphenyl cyclopentenyl hydroxyureas | PFIZER INC. (US) | 1998-08-11 | — | — | US | disclosed |
| CN-1129440-A | Phenoxyphenyl cyclopentenyl hydroxyureas | PFIZER (JP) | 1996-08-21 | — | — | CN | disclosed |
| CN-1129440-A | Phenoxyphenyl cyclopentenyl hydroxyureas | PFIZER (JP) | 1996-08-21 | — | — | CN | disclosed |