SCHEMBL5280286

SCHEMBL5280286

CCCCN(CCCC)c1ccc(C(=O)OC)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.59
NPC1 O15118 2/20 0.54
CASP1 P29466 1/20 0.54
RAB9A P51151 1/20 0.54
EGFR P00533 1/20 0.54
ERBB2 P04626 1/20 0.54
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
MGLL Q99685 1/20 0.48
MAPT P10636 3/20 0.48
ALDH1A1 P00352 2/20 0.48
GAA P10253 2/20 0.48
KDM4E B2RXH2 1/20 0.48
HPGD P15428 1/20 0.48
TSHR P16473 1/20 0.48
MAPK1 P28482 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
HSD17B10 Q99714 1/20 0.48
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8649876 0.90 MEN1 (0.51) L3MBTL1NPC1CASP1RAB9AEGFR
SCHEMBL8373743 0.90 L3MBTL1 (0.56) L3MBTL1NPC1CASP1RAB9AEGFR
SCHEMBL15704245 0.85 L3MBTL1 (0.58) L3MBTL1NPC1CASP1RAB9AMGLL
SCHEMBL8602388 0.85 ESR1 (0.54) L3MBTL1NPC1RAB9AEGFRERBB2
SCHEMBL11665682 0.85 L3MBTL1 (0.55) L3MBTL1NPC1CASP1RAB9AMEN1
SCHEMBL13253174 0.83 ALDH1A1 (0.60) NPC1MEN1KMT2AMAPTALDH1A1
SCHEMBL1827424 0.82 EGFR (0.59) NPC1RAB9AEGFRERBB2MAPT
SCHEMBL65794 0.82 MAPT (0.61) NPC1MEN1KMT2AMAPTALDH1A1
Hexane SCHEMBL28004600 0.82 MGLL (0.63) NPC1CASP1RAB9AMEN1KMT2A
SCHEMBL11801026 0.81 L3MBTL1 (0.48) L3MBTL1RAB9AMAPTALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116924916-A Method for synthesizing tertiary amine and secondary amine by high-selectivity aldehyde reductive amination under catalyst-free condition 西南石油大学 2023-10-24 CN disclosed
EP-1313560-B1 CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION UNIV YALE (US) 2007-12-19 EP disclosed
US-6562989-B2 Bicyclopentyl iron ligand and transition metal catalyst YALE UNIVERSITY 2003-05-13 US disclosed
US-20030008768-A1 Catalyst for aromatic C-O, C-N, and C-C bond formation NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-01-09 US disclosed