Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5280296 | 0.84 | SLC9A1 (0.37) | SLC9A1ADORA2AADORA2BALDH1A1KDM4E | |
| SCHEMBL5278792 | 0.81 | SLC9A1 (0.40) | SLC9A1ALDH1A1GRM2 | |
| SCHEMBL5281303 | 0.79 | ALDH1A1 (0.33) | CYP11B2SLC9A1NPC1ALDH1A1GRM2 | |
| SCHEMBL5277604 | 0.78 | SLC9A1 (0.43) | SLC9A1ALDH1A1KDM4EGRM2 | |
| SCHEMBL5283619 | 0.78 | SLC9A1 (0.32) | CYP11B2SLC9A1NPC1 | |
| SCHEMBL5277792 | 0.78 | GRM2 (0.36) | CYP11B2SLC9A1NPC1GRM2 | |
| SCHEMBL5281690 | 0.78 | MAOA (0.34) | CYP11B2SLC9A1NPC1MAOA | |
| SCHEMBL5274087 | 0.78 | SLC9A1 (0.32) | CYP11B2SLC9A1NPC1 | |
| SCHEMBL5284267 | 0.75 | MAOA (0.36) | SLC9A1NPC1MAOAALDH1A1KDM4E | |
| SCHEMBL5276538 | 0.75 | SLC9A1 (0.31) | SLC9A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |