SCHEMBL5280370

SCHEMBL5280370

O=C(CO)OCCc1cc(Cc2cc(CCOC(=O)CO)cc(-n3nc4ccccc4n3)c2O)c(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.37
NPC1 O15118 5/20 0.36
RAB9A P51151 5/20 0.36
POLB P06746 3/20 0.36
KDM4E B2RXH2 5/20 0.35
ALDH1A1 P00352 5/20 0.35
HPGD P15428 4/20 0.35
ALOX15 P16050 1/20 0.35
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MAPT P10636 3/20 0.35
LMNA P02545 2/20 0.35
APP P05067 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
TDP1 Q9NUW8 3/20 0.34
NPSR1 Q6W5P4 1/20 0.33
YWHAG P61981 1/20 0.33
TYR P14679 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5276858 0.92 ALOX5 (0.41) ALOX5NPC1RAB9APOLBKDM4E
SCHEMBL5274127 0.89 ALOX5 (0.39) ALOX5NPC1RAB9APOLBKDM4E
SCHEMBL6753078 0.87 ALOX5 (0.38) ALOX5NPC1RAB9APOLBKDM4E
SCHEMBL5274144 0.86 ALOX5 (0.37) ALOX5NPC1RAB9APOLBKDM4E
SCHEMBL6753230 0.86 ALOX5 (0.37) ALOX5NPC1RAB9APOLBKDM4E
SCHEMBL5276127 0.86 ALOX5 (0.37) ALOX5NPC1RAB9APOLBKDM4E
SCHEMBL7736256 0.84 THRB (0.40) ALOX5NPC1RAB9APOLBKDM4E
SCHEMBL7736250 0.84 NPC1 (0.37) ALOX5NPC1RAB9APOLBKDM4E
SCHEMBL342550 0.81 KDM4E (0.46) ALOX5NPC1RAB9APOLBKDM4E
SCHEMBL30112936 0.81 KDM4E (0.46) ALOX5NPC1RAB9APOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1125764-B1 TRANSFER MATERIAL, SURFACE-PROTECTIVE SHEET, AND PROCESS FOR PRODUCING MOLDED ARTICLE WITH THESE NISSHA PRINTING (JP) 2007-12-05 EP disclosed
US-6703139-B1 BISBENZOTRIAZOLYLPHENOL COMPOUND AS AN ULTRAVIOLET ABSORBER OTSUKA CHEMICAL CO., LTD. (JP) 2004-03-09 US disclosed
US-6527898-B1 Protective layer comprising active energy ray curable resin obtained by heat-crosslinking a heat and active energy ray curable resin; a polyfunctional isocyanate; and a UV absorber; NISSHA PRINTING CO., LTD. (JP) 2003-03-04 US disclosed
EP-1125764-A1 TRANSFER MATERIAL, SURFACE-PROTECTIVE SHEET, AND PROCESS FOR PRODUCING MOLDED ARTICLE WITH THESE NISSHA PRINTING CO., LTD. (JP) 2001-08-22 EP disclosed
EP-1104790-A1 WEATHER-RESISTANT COMPOSITION, COATING MATERIALS AND MOLDED ARTICLES OTSUKA CHEMICAL COMPANY, LIMITED (JP) 2001-06-06 EP disclosed