Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 5/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7027917 | 0.95 | THRB (0.36) | THRBNPC1RAB9AHCAR2AKR1B10 | |
| SCHEMBL7024606 | 0.94 | NPC1 (0.43) | THRBNPC1RAB9AAKR1B10AKR1B1 | |
| SCHEMBL7032209 | 0.88 | NPC1 (0.42) | THRBNPC1RAB9AAKR1B10AKR1B1 | |
| SCHEMBL7737093 | 0.88 | THRB (0.36) | THRBNPC1RAB9AHCAR2AKR1B10 | |
| SCHEMBL27503098 | 0.87 | THRB (0.38) | THRBNPC1RAB9AHCAR2AKR1B10 | |
| SCHEMBL2777975 | 0.87 | NPC1 (0.40) | THRBNPC1RAB9AHCAR2AKR1B10 | |
| SCHEMBL7033730 | 0.86 | ALOX5 (0.34) | THRBNPC1RAB9AAKR1B10AKR1B1 | |
| SCHEMBL5280370 | 0.84 | ALOX5 (0.37) | NPC1RAB9AALOX5POLBALDH1A1 | |
| SCHEMBL25409880 | 0.84 | GAA (0.39) | THRBNPC1RAB9AAKR1B10AKR1B1 | |
| SCHEMBL7736250 | 0.84 | NPC1 (0.37) | THRBNPC1RAB9AALOX5POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414100-B1 | COMPOUND HAVING EXTREMELY LOW VAPOR PRESSURE AND HIGH DECOMPOSITION TEMPERATURE; CROSSLINKING AGENT FOR WEATHER RESISTANT POLYMERS | OTSUKA CHEMICAL CO., LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| EP-1055669-A1 | BISBENZOTRIAZOLYLPHENOL COMPOUNDS, ULTRAVIOLET ABSORBER, ULTRAVIOLET-ABSORBING POLYMER, AND RESIN COMPOSITION AND COATING MATERIAL BOTH CONTAINING THESE | OTSUKA CHEMICAL COMPANY, LIMITED (JP) | 2000-11-29 | — | — | EP | disclosed |