Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL30449157 | 0.77 | TBXAS1 (0.50) | TBXAS1CSNK1A1TYRO3DYRK1B | |
| Succinic Acid SCHEMBL25280176 | 0.77 | TBXAS1 (0.50) | TBXAS1CSNK1A1TYRO3DYRK1B | |
| Succinic Acid SCHEMBL30449098 | 0.77 | TBXAS1 (0.50) | TBXAS1CSNK1A1TYRO3DYRK1B | |
| Carbamic Acid SCHEMBL6394464 | 0.74 | CSNK1A1 (0.41) | TBXAS1CSNK1A1TYRO3DYRK1B | |
| Formic Acid SCHEMBL27660664 | 0.74 | — | — | |
| Bicarbonate SCHEMBL5521423 | 0.72 | ALDH1A1 (0.41) | TBXAS1CSNK1A1TYRO3DYRK1B | |
| Formamide SCHEMBL28418583 | 0.72 | — | — | |
| Imidazole SCHEMBL5957152 | 0.72 | ALDH1A1 (0.42) | — | |
| SCHEMBL168 | 0.70 | — | — | |
| SCHEMBL28949843 | 0.70 | ALDH1A1 (0.46) | CSNK1A1TYRO3DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030166201-A1 | Selection systems for genetically modified cells | CITY OF HOPE | 2003-09-04 | — | — | US | claimed |
| EP-0405370-B2 | Riboflavinoverproducing strains of bacteria | DSM IP ASSETS BV (NL) | 2007-12-19 | — | — | EP | disclosed |
| US-7091000-B2 | Bacterial strains which overproduce riboflavin and methods of use thereof | DSM NUTRITIONAL PRODUCTS, INC. (US) | 2006-08-15 | — | — | US | disclosed |
| US-20030166201-A1 | Selection systems for genetically modified cells | CITY OF HOPE | 2003-09-04 | — | — | US | disclosed |
| US-6322995-B1 | RECOMBINANT GRAM POSITIVE BACTERIUM USED FOR PRODUCING RIBOFLAVIN | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-27 | — | — | US | disclosed |
| EP-0405370-B1 | Riboflavinoverproducing strains of bacteria | HOFFMANN LA ROCHE (CH) | 2000-08-30 | — | — | EP | disclosed |
| EP-1001026-A2 | Riboflavinoverproducing strains of bacteria | F. Hoffmann-La Roche AG (CH) | 2000-05-17 | — | — | EP | disclosed |
| US-5925538-A | CULTURING RECOMBINANT BACTERIUM HAVING EXOGENOUS NUCLEIC ACID SEQUENCE CODING FOR PROMOTER AND OPEN READING FRAME 3 STRUCTURAL GENE SIMILAR TO A BACILLUS SUBTILIS RIBOFLAVIN OPERON GENE, RECOVERING AT LEAST 10 GRAMS PER LITER | ROCHE VITAMINS INC. (US) | 1999-07-20 | — | — | US | disclosed |
| US-5837528-A | NUCLEOTIDE SEQUENCE OF RIB OPERON AND ITS OPEN READING FRAMES; GENETIC ENGINEERING | HOFFMANN LA ROCHE, INC. (US) | 1998-11-17 | — | — | US | disclosed |
| US-5204252-A | Having auxotropic host, requiring uracil for growth, fusing with DNA constructs with genes encoding enzymes which complement auxotrophies to prototrophies; means for screening fungicides | HENKEL RESEARCH CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |
| EP-0457852-A1 | CANDIDA TROPICALIS TRANSFORMATION SYSTEM | HENKEL RESEARCH CORPORATION (US) | 1991-11-27 | — | — | EP | disclosed |
| EP-0405370-A1 | Riboflavinoverproducing strains of bacteria | F. HOFFMANN-LA ROCHE AG (CH) | 1991-01-02 | — | — | EP | disclosed |
| WO-1990009449-A2 | CANDIDA TROPICALIS TRANSFORMATION SYSTEM | HENKEL RESEARCH CORPORATION (US) | 1990-08-23 | — | — | WO | disclosed |