Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 8/20 | 0.42 |
| ▸ | THRA | P10827 | 5/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5278260 | 0.91 | KDM4E (0.50) | KDM4EGAAALDH1A1THRBTHRA | |
| SCHEMBL5277821 | 0.88 | KDM4E (0.47) | KDM4EGAAALDH1A1THRBTHRA | |
| SCHEMBL5279829 | 0.88 | GAA (0.46) | KDM4EGAAALDH1A1THRBTHRA | |
| SCHEMBL5278322 | 0.84 | CYP3A4 (0.44) | KDM4EGAAALDH1A1THRBTHRA | |
| SCHEMBL5279511 | 0.83 | THRB (0.46) | KDM4EGAAALDH1A1THRBTHRA | |
| SCHEMBL5284091 | 0.82 | RORC (0.60) | KDM4EGAATHRBTHRAPKM | |
| SCHEMBL5279235 | 0.81 | THRA (0.66) | THRBTHRA | |
| SCHEMBL5278084 | 0.79 | KDM4E (0.44) | KDM4EGAAALDH1A1THRBTHRA | |
| SCHEMBL4440700 | 0.78 | KDM4E (0.51) | KDM4EGAAALDH1A1THRBTHRA | |
| SCHEMBL5280401 | 0.76 | THRB (0.43) | KDM4EGAAALDH1A1THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1862450-A2 | Novel compounds | KARO BIO AB (SE) | 2007-12-05 | — | — | EP | disclosed |
| EP-1537073-B1 | BENZAMIDE OR PHENYLACETAMIDE DERIVATIVES USEFUL AS THYROID RECEPTOR LIGANDS | KAROBIO AB (SE) | 2007-09-12 | — | — | EP | disclosed |
| US-7153997-B2 | Benzamide derivatives as thyroid receptor ligands | KARO BIO AB (SE) | 2006-12-26 | — | — | US | disclosed |
| US-20060135614-A1 | Novel compounds | NORIN, THOMAS ANDERS WILSON (SE) | 2006-06-22 | — | — | US | disclosed |
| EP-1537073-A2 | BENZAMIDE OR PHENYLACETAMIDE DERIVATIVES USEFUL AS THYROID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004007430-A2 | BENZAMIDE OR PHENYLACETAMIDE DERIVATIVES USEFUL AS THYROID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2004-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135614-A1 | Novel compounds | THRB, TSHR, THRA | KDM4E 4069/4885GAA 3139/4885ALDH1A1 1777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.