Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5279898 | 0.87 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL5284361 | 0.87 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTBLMKMT2A | |
| SCHEMBL5275582 | 0.85 | ALDH1A1 (0.32) | ALDH1A1LMNAMAPTBLMKMT2A | |
| SCHEMBL5274455 | 0.84 | SLC9A1 (0.35) | ALDH1A1LMNAMAPTBLMKMT2A | |
| SCHEMBL5278562 | 0.83 | ALDH1A1 (0.31) | ALDH1A1LMNAMAPTBLMKMT2A | |
| SCHEMBL5280072 | 0.82 | SLC9A1 (0.38) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL5282480 | 0.81 | — | — | |
| SCHEMBL5283924 | 0.79 | PKM (0.34) | ALDH1A1LMNAMAPTBLMKMT2A | |
| SCHEMBL5279772 | 0.77 | SMN1; SMN2 (0.36) | ALDH1A1LMNAMAPTBLMKMT2A | |
| SCHEMBL5281132 | 0.75 | SMN1; SMN2 (0.36) | ALDH1A1LMNAMAPTBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |