SCHEMBL5280901

SCHEMBL5280901

COC1(C)CN(c2c(F)cc(N)cc2F)C1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAP3K12 Q12852 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL240685 0.82 ALDH1A1 (0.31)
SCHEMBL5287503 0.79 SOS1 (0.31)
SCHEMBL5289445 0.78 ALDH1A1 (0.38)
SCHEMBL4707905 0.76 ALDH1A1 (0.32)
SCHEMBL239677 0.71 MAPT (0.33)
SCHEMBL18410289 0.70 LRRK2 (0.44)
SCHEMBL5282437 0.70 ACACB (0.36) MAP3K12
SCHEMBL14320939 0.69 MAPT (0.46)
SCHEMBL4703571 0.69 ALOX5AP (0.33)
SCHEMBL28554928 0.68 MAPT (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007004049-A1 OXAZOLIDINONES CONTAINING AZETIDINE AS ANTIBACTERIAL AGENTS PHARMACIA & UPJOHN COMPANY LLC (US) 2007-01-11 WO disclosed