Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | MAP3K12 | Q12852 | 3/20 | 0.31 |
| ▸ | RXRA | P19793 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5284741 | 0.81 | ACACB (0.37) | ACACBCNR2 | |
| SCHEMBL4706606 | 0.77 | MAOA (0.33) | MAOA | |
| SCHEMBL236762 | 0.76 | KDM4E (0.35) | MAOA | |
| SCHEMBL5281743 | 0.76 | ALDH1A1 (0.38) | ACACBCNR2 | |
| SCHEMBL238837 | 0.76 | MAOA (0.32) | ACACBMAOA | |
| SCHEMBL239087 | 0.76 | MAOA (0.32) | ACACBMAOA | |
| SCHEMBL29209046 | 0.75 | KDM4E (0.46) | MAOA | |
| SCHEMBL240100 | 0.75 | KDM4E (0.46) | MAOA | |
| SCHEMBL3563045 | 0.75 | SCN9A (0.38) | MAOAKCNH2 | |
| SCHEMBL6209260 | 0.74 | MAOA (0.34) | MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007004049-A1 | OXAZOLIDINONES CONTAINING AZETIDINE AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-01-11 | — | — | WO | disclosed |