Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5280121 | 1.00 | CYP2C19 (0.51) | CYP2C19HTTHPGDCYP2C9CYP1A2 | |
| SCHEMBL14582256 | 0.89 | MTNR1A (0.45) | CYP2C19HTTHPGDCYP2C9CYP1A2 | |
| SCHEMBL657068 | 0.88 | HPGD (0.54) | CYP2C19HTTHPGDCYP2C9CYP1A2 | |
| SCHEMBL656946 | 0.88 | HPGD (0.62) | CYP2C19HTTHPGDCYP2C9CYP1A2 | |
| SCHEMBL14582250 | 0.84 | HTT (0.55) | CYP2C19HTTHPGDCYP2C9CYP1A2 | |
| SCHEMBL3814689 | 0.82 | CYP2C9 (0.56) | CYP2C19HTTHPGDCYP2C9CYP1A2 | |
| SCHEMBL7686449 | 0.81 | CYP2C19 (0.41) | CYP2C19HTTHPGDCYP2C9CYP1A2 | |
| SCHEMBL28754169 | 0.81 | CYP2C19 (0.48) | CYP2C19HTTHPGDCYP2C9CYP1A2 | |
| SCHEMBL5829435 | 0.81 | CYP2C19 (0.48) | CYP2C19HTTHPGDCYP2C9CYP1A2 | |
| SCHEMBL9807303 | 0.79 | HPGD (0.54) | CYP2C19HTTHPGDCYP2C9CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918754-B1 | ANTHRANILIC ACID DIAMIDES DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL USE AS ANTI-GASTRIN AGENTS | ROTTAPHARM SPA (IT) | 2007-12-05 | — | — | EP | claimed |
| US-6075033-A | Anthranilic acid diamides derivatives, their preparation and pharmaceutical use as anti-gastrin agents | ROTTA RESEARCH LABORATORIUM S.P.A (IT) | 2000-06-13 | — | — | US | claimed |