SCHEMBL5281037

SCHEMBL5281037

CC(=O)Nc1cccc(N(CCOC(C)=O)CCOC(C)=O)c1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.47
POLB P06746 1/20 0.47
NR4A1 P22736 1/20 0.47
ALDH1A1 P00352 2/20 0.46
CYP1A2 P05177 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MAPT P10636 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
NPC1 O15118 2/20 0.44
HTR7 P34969 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
AHR P35869 1/20 0.42
MTNR1A P48039 2/20 0.41
MTNR1B P49286 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11049552 0.93 RAB9A (0.47) RAB9APOLBNR4A1ALDH1A1CYP1A2
SCHEMBL29995761 0.91 HSD17B10 (0.43) RAB9APOLBNR4A1ALDH1A1CYP1A2
SCHEMBL28604505 0.91 HSD17B10 (0.43) RAB9APOLBNR4A1ALDH1A1CYP1A2
SCHEMBL11327861 0.90 RAB9A (0.46) RAB9APOLBNR4A1ALDH1A1CYP1A2
SCHEMBL11044870 0.89 MTNR1A (0.52) RAB9AALDH1A1MAPTKMT2AMEN1
SCHEMBL10893092 0.88 POLB (0.54) RAB9APOLBNR4A1ALDH1A1CYP1A2
SCHEMBL11417512 0.88 TP53 (0.49) ALDH1A1
SCHEMBL11339398 0.88 KMT2A (0.48) RAB9APOLBNR4A1ALDH1A1CYP1A2
SCHEMBL11044442 0.88 HTR7 (0.52) RAB9APOLBNR4A1ALDH1A1CYP1A2
SCHEMBL2009452 0.87 MTNR1A (0.48) RAB9APOLBNR4A1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718376-B1 Colour-fast monoazo dye, its manufacture and its use DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-07-18 EP claimed
EP-0718376-A1 Colour-fast monoazo dye, its manufacture and its use DyStar Japan Ltd. (JP) 1996-06-26 EP claimed
CN-112940523-B Continuous coupling reaction integrated device and application 沈阳化工研究院有限公司 2022-06-14 CN disclosed
CN-111744435-B Esterification process of hydroxylate 浙江汇翔新材料科技股份有限公司 2022-04-01 CN disclosed
EP-1466947-B1 AZO compound CLARIANT FINANCE BVI LTD (VG) 2007-12-19 EP disclosed
US-7301013-B2 Azo compounds CLARIANT FINANCE (BVI) LIMITED (GB) 2007-11-27 US disclosed
US-20060258854-A1 Azo compounds CLARIANT FINANCE (BVI) LIMITED 2006-11-16 US disclosed
US-7101983-B2 Azo dyes CLARIANT FINANCE (BVI) LIMITED (VG) 2006-09-05 US disclosed
EP-1377641-B1 AZO DYES CLARIANT FINANCE BVI LTD (VG) 2005-09-07 EP disclosed
EP-1466947-A1 AZO compound Clariant Finance (BVI) Limited (VG) 2004-10-13 EP disclosed
US-20040143108-A1 Azo dyes CLARIANT FINANCE (BVI) LIMITED (VG) 2004-07-22 US disclosed
US-4153413-A DYEING POLYESTER OR CELLULOSE TRIACETATE WITH A DISPERSE AZO DYESTUFF, HEAT TREATMENT, PADDING, PRINTING IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-05-08 US disclosed
US-4039522-A Phthalimidyl-azo-m-acylamido-n-substituted aniline compounds and polyester fibers dyed therewith EASTMAN KODAK COMPANY (US) 1977-08-02 US disclosed
US-4036824-A Disazo dyestuffs containing A-O-alkylene-O-SO3 H group BAYER AKTIENGESELLSCHAFT (DT) 1977-07-19 US disclosed
US-4022763-A Sulfaphenyl-azo-phenyl-azo-aminophenyl dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-05-10 US disclosed
US-4013632-A SYNTHETIC FIBERS PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-03-22 US disclosed
US-3998805-A MONOAZO DYES; POLYESTERS; YELLOW, RED, OR ORANGE SHADES CIBA-GEIGY CORPORATION (US) 1976-12-21 US disclosed
US-3978039-A POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-08-24 US disclosed
US-3966703-A Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US disclosed
US-3951592-A Polyester fabric materials dyed with monoazo dyes made from 4-amino-7-nitrobenzotriazole AMERICAN COLOR & CHEMICAL CORPORATION (US) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060258854-A1 Azo compounds CYP1B1, TYR, CYP1A1 RAB9A 4424/4885POLB 4208/4885NR4A1 220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.