SCHEMBL5281104

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2988478	0.83	ALDH1A1 (0.53)	ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19
	SCHEMBL5281106	0.83	MAPT (0.62)	ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19
	SCHEMBL27410200	0.81	CYP1A2 (0.51)	ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19
	SCHEMBL9313579	0.79	ALDH1A1 (0.61)	ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19
	SCHEMBL10882419	0.75	MGLL (0.56)	ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19
	SCHEMBL2308066	0.74	ALDH1A1 (0.61)	ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19
	SCHEMBL15677251	0.73	MEN1 (0.74)	ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19
	SCHEMBL5954207	0.73	ALDH1A1 (0.50)	ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19
	SCHEMBL7912447	0.72	MGLL (0.52)	ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19
	SCHEMBL28468319	0.72	KMT2A (0.55)	ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.