SCHEMBL5281186

SCHEMBL5281186

NC(=O)CC(NC(=O)Cn1ccc2ccccc21)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NTSR1 P30989 14/20 0.70
KMT2A Q03164 1/20 0.54
LMNA P02545 1/20 0.50
ITGB2 P05107 1/20 0.46
ICAM1 P05362 1/20 0.46
ITGAL P20701 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5275345 0.88 NTSR1 (0.67) NTSR1KMT2ALMNA
SCHEMBL6138168 0.86 NTSR1 (0.75) NTSR1KMT2A
SCHEMBL6138085 0.79 NTSR1 (0.73) NTSR1KMT2A
SCHEMBL29955957 0.76 KMT2A (0.71) NTSR1KMT2ALMNA
SCHEMBL1519806 0.76 KMT2A (0.71) NTSR1KMT2ALMNA
SCHEMBL6138201 0.76 NTSR1 (0.68) NTSR1KMT2A
SCHEMBL7876613 0.75 KMT2A (0.65) NTSR1KMT2ALMNA
Acetic Acid SCHEMBL27760597 0.74 KMT2A (0.68) NTSR1KMT2ALMNA
SCHEMBL3307080 0.74 KMT2A (0.68) NTSR1KMT2ALMNA
SCHEMBL2593474 0.72 KMT2A (0.65) NTSR1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1052968-B1 ALPHA-AMIDES OF(L)-AMINO ACIDS AS FRAGRANCE PRECURSORS GILLETTE CO (US) 2007-12-05 EP claimed
EP-1052968-A4 $g(a)-AMIDES OF $i(L)-AMINO ACIDS AS FRAGRANCE PRECURSORS GILLETTE CO (US) 2004-09-15 EP claimed
EP-1052968-A1 $g(a)-AMIDES OF $i(L)-AMINO ACIDS AS FRAGRANCE PRECURSORS THE GILLETTE COMPANY (US) 2000-11-22 EP claimed
US-5932198-A α-amides of L-amino acids as fragrance precursors THE GILLETTE COMPANY (US) 1999-08-03 US claimed
WO-1999030680-A1 α-AMIDES OF L-AMINO ACIDS AS FRAGRANCE PRECURSORS THE GILLETTE COMPANY (US) 1999-06-24 WO claimed
EP-1052968-B1 ALPHA-AMIDES OF(L)-AMINO ACIDS AS FRAGRANCE PRECURSORS GILLETTE CO (US) 2007-12-05 EP disclosed
US-5932198-A α-amides of L-amino acids as fragrance precursors THE GILLETTE COMPANY (US) 1999-08-03 US disclosed