Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 9/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5272930 | 0.88 | SPHK2 (0.34) | MEN1KMT2A | |
| SCHEMBL5278178 | 0.86 | ALDH1A1 (0.35) | — | |
| SCHEMBL5276249 | 0.86 | SMYD2 (0.33) | CHEK1 | |
| SCHEMBL5801918 | 0.85 | P2RY12 (0.34) | CHEK1 | |
| SCHEMBL4695001 | 0.83 | CD274 (0.46) | — | |
| SCHEMBL5803928 | 0.83 | MAOB (0.35) | — | |
| SCHEMBL4695640 | 0.82 | PDCD1 (0.34) | ACKR3 | |
| SCHEMBL5810881 | 0.81 | SMN1; SMN2 (0.37) | CHEK1 | |
| SCHEMBL4695511 | 0.80 | PDCD1 (0.34) | — | |
| SCHEMBL5276039 | 0.79 | PDCD1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856048-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | Theravance, Inc. (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006098999-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE, INC. (US) | 2006-09-21 | — | — | WO | disclosed |