Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5272930 | 0.87 | SPHK2 (0.34) | LMNACD274 | |
| SCHEMBL5803928 | 0.87 | MAOB (0.35) | NTRK1CD274 | |
| SCHEMBL5276249 | 0.87 | SMYD2 (0.33) | LMNAHTR7CD274CHEK1 | |
| SCHEMBL5281205 | 0.85 | ACKR3 (0.32) | CHEK1 | |
| SCHEMBL5278178 | 0.85 | ALDH1A1 (0.35) | — | |
| SCHEMBL5810881 | 0.82 | SMN1; SMN2 (0.37) | LMNAHTR7CHEK1 | |
| SCHEMBL4695511 | 0.81 | PDCD1 (0.34) | CD274 | |
| SCHEMBL5277443 | 0.80 | SMN1; SMN2 (0.34) | HTR7CD274 | |
| SCHEMBL5722183 | 0.78 | HPGD (0.40) | LMNACD274 | |
| SCHEMBL4696348 | 0.77 | PDCD1 (0.38) | HTR7CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006098997-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE, INC. (US) | 2006-09-21 | — | — | WO | disclosed |