Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21401067 | 0.80 | KMT2A (0.52) | POLBP2RX7SMN1; SMN2NPC1KMT2A | |
| SCHEMBL5293773 | 0.76 | TAAR1 (0.68) | HPGDALDH1A1HTTGAA | |
| SCHEMBL5843237 | 0.76 | MAPK8 (0.50) | POLBP2RX7SMN1; SMN2NPC1KMT2A | |
| SCHEMBL3668726 | 0.74 | MEN1 (0.50) | POLBSMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL5298479 | 0.74 | NPC1 (0.53) | POLBP2RX7SMN1; SMN2NPC1KMT2A | |
| Acetic Acid SCHEMBL10537361 | 0.73 | TAAR1 (0.64) | SMN1; SMN2HPGDALDH1A1HTTGAA | |
| SCHEMBL25046059 | 0.73 | ALDH1A1 (0.65) | POLBSMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL5294169 | 0.73 | AKR1B1 (0.54) | POLBP2RX7SMN1; SMN2NPC1KMT2A | |
| SCHEMBL23903302 | 0.73 | POLB (0.64) | POLBCYP2C19SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5298485 | 0.72 | NPC1 (0.54) | POLBP2RX7SMN1; SMN2NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | claimed |
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |