Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22170167 | 0.81 | TAAR1 (0.67) | POLBCYP2C19HPGDNPC1RAB9A | |
| SCHEMBL10789439 | 0.79 | CNR1 (0.71) | POLBCYP2C19L3MBTL1LMNAPKM | |
| SCHEMBL23903309 | 0.76 | LMNA (0.52) | POLBCYP2C19L3MBTL1LMNAPKM | |
| SCHEMBL26724889 | 0.74 | GABRA1 (0.50) | POLBL3MBTL1LMNA | |
| SCHEMBL3808149 | 0.74 | AKR1B1 (0.55) | — | |
| SCHEMBL10125651 | 0.74 | HPGD (0.66) | LMNAHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL19688866 | 0.73 | GABRA1 (0.46) | POLBL3MBTL1LMNAKCNA5HPGD | |
| SCHEMBL9635048 | 0.73 | ALDH1A1 (0.47) | CYP2C19L3MBTL1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL15434628 | 0.73 | MTNR1A (0.49) | HPGDNPC1HTT | |
| Bicarbonate SCHEMBL27568192 | 0.73 | GABRA1 (0.58) | L3MBTL1LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021203016-A2 | PROTEIN-PROTEIN INTERACTION STABILIZERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-10-07 | — | — | WO | disclosed |