Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21401067 | 0.82 | KMT2A (0.52) | MAPK8NPC1SMN1; SMN2KMT2APOLB | |
| SCHEMBL6876231 | 0.81 | TAAR1 (0.67) | MAPK8NPC1KMT2APOLBMEN1 | |
| SCHEMBL5293773 | 0.78 | TAAR1 (0.68) | ALDH1A1HPGDHTTLMNAGAA | |
| SCHEMBL158861 | 0.77 | CTBP2 (0.55) | MAPK8NPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL29718576 | 0.77 | CTBP2 (0.55) | MAPK8NPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL5842518 | 0.77 | ATM (0.65) | SMN1; SMN2KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL1244426 | 0.76 | ALDH1A1 (0.64) | NPC1SMN1; SMN2KMT2APOLBMEN1 | |
| SCHEMBL11550242 | 0.76 | MAPK8 (0.54) | MAPK8NPC1SMN1; SMN2KMT2APOLB | |
| Acetic Acid SCHEMBL10537361 | 0.76 | TAAR1 (0.64) | SMN1; SMN2ALDH1A1HPGDHTTLMNA | |
| SCHEMBL5281267 | 0.76 | POLB (0.51) | MAPK8NPC1SMN1; SMN2KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109243-B2 | Inhibitors of cathepsin S | IRM LLC (BM) | 2006-09-19 | — | — | US | claimed |