Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 5/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4950009 | 0.85 | HTR1A (0.43) | HTR1ADRD2HTR2A | |
| SCHEMBL4950230 | 0.83 | DRD2 (0.42) | HTR1ADRD2HTR2A | |
| SCHEMBL4945985 | 0.83 | DRD2 (0.43) | HTR1ADRD2HTR2A | |
| SCHEMBL4951231 | 0.81 | DRD2 (0.42) | HTR1ADRD2HTR2A | |
| SCHEMBL4945980 | 0.81 | HTR1A (0.42) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL4949496 | 0.80 | HTR1A (0.40) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL5281277 | 0.79 | HTR1A (0.35) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL5138357 | 0.78 | DRD2 (0.37) | HTR1ADRD2HTR2A | |
| SCHEMBL5089717 | 0.76 | DRD2 (0.38) | HTR1ADRD2HTR2A | |
| SCHEMBL4945746 | 0.74 | HTR1A (0.43) | HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761524-B1 | PHENYL DIAZEPANE CARBOXAMIDES AND ANNELATED PHENYL PIPERAZINE CARBOXAMIDES CONTAINING OXYGEN AND USED AS DOPAMINE D3 ANTAGONISTS | SANOL ARZNEI SCHWARZ GMBH (DE) | 2007-11-21 | — | — | EP | disclosed |