Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4950012 | 0.85 | HTR1A (0.46) | HTR1ADRD2HTR2A | |
| SCHEMBL4950232 | 0.83 | HTR1A (0.46) | HTR1ADRD2HTR2A | |
| SCHEMBL4945988 | 0.83 | HTR1A (0.46) | HTR1ADRD2HTR2A | |
| SCHEMBL4951238 | 0.81 | HTR1A (0.46) | HTR1ADRD2HTR2A | |
| SCHEMBL4945982 | 0.81 | HTR1A (0.44) | HTR1ADRD2HTR2A | |
| SCHEMBL4949501 | 0.80 | HTR1A (0.46) | HTR1ADRD2HTR2A | |
| SCHEMBL5281270 | 0.79 | ADRA1D (0.34) | HTR1AADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL4951024 | 0.71 | HTR1A (0.43) | HTR1ADRD2HTR2A | |
| SCHEMBL4945898 | 0.71 | DRD2 (0.42) | HTR1AADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL4945969 | 0.70 | HTR7 (0.39) | HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761524-B1 | PHENYL DIAZEPANE CARBOXAMIDES AND ANNELATED PHENYL PIPERAZINE CARBOXAMIDES CONTAINING OXYGEN AND USED AS DOPAMINE D3 ANTAGONISTS | SANOL ARZNEI SCHWARZ GMBH (DE) | 2007-11-21 | — | — | EP | disclosed |