SCHEMBL528130

SCHEMBL528130

c1cnnc2c(c1)ccc1nnnc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.40
CCR1 P32246 3/20 0.40
CCR5 P51681 3/20 0.40
CCR8 P51685 3/20 0.40
CYP3A4 P08684 2/20 0.40
MMP2 P08253 2/20 0.40
TSHR P16473 2/20 0.40
KDM4E B2RXH2 1/20 0.40
GMNN O75496 1/20 0.40
TP53 P04637 1/20 0.40
HSP90AA1 P07900 1/20 0.40
CYP2D6 P10635 1/20 0.40
MAPT P10636 1/20 0.40
MMP9 P14780 1/20 0.40
ALOX15 P16050 1/20 0.40
NFKB1 P19838 1/20 0.40
MMP8 P22894 1/20 0.40
THPO P40225 1/20 0.40
MTOR P42345 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylamine SCHEMBL11033934 0.90 HTR2A (0.34) LMNACCR1CCR5CCR8CYP3A4
SCHEMBL17511986 0.84 LMNA (0.31) LMNA
SCHEMBL11499049 0.82 LMNA (0.31) LMNACCR1CCR5CCR8CYP3A4
SCHEMBL3586683 0.78 CCR1 (0.64) LMNACCR1CCR5CCR8CYP3A4
SCHEMBL1451059 0.77 LMNA (0.56) LMNACCR1CCR5CCR8CYP3A4
SCHEMBL194481 0.76 LMNA (0.43) LMNACCR1CCR5CCR8CYP3A4
SCHEMBL8673305 0.74 LMNA (0.37) LMNACYP3A4KDM4EMAPTHTT
SCHEMBL3820324 0.72 LMNA (0.43) LMNACCR1CCR5CCR8CYP3A4
SCHEMBL21001801 0.72 LMNA (0.61) LMNACCR1CCR5CCR8CYP3A4
SCHEMBL157930 0.72 LMNA (0.61) LMNACCR1CCR5CCR8CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 459 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250073207-A1 PSILOCIN BENZOATE FORMULATION FOR INTRAVENOUS INFUSION ELEUSIS THERAPEUTICS US, INC. 2025-03-06 US claimed
EP-4463153-A1 PSILOCIN BENZOATE FORMULATION FOR INTRAVENOUS INFUSION Eleusis Therapeutics US, Inc. (US) 2024-11-20 EP claimed
CN-118108723-A Triazolobenzodiazepine compound and preparation method and application thereof 暨南大学附属第一医院(广州华侨医院) 2024-05-31 CN claimed
US-20230277568-A1 METHOD OF TREATMENT FOR PSILOCYBIN OR PSILOCIN INFUSION ELEUSIS THERAPEUTICS US, INC. 2023-09-07 US claimed
WO-2023137094-A1 PSILOCIN BENZOATE FORMULATION FOR INTRAVENOUS INFUSION ELEUSIS THERAPEUTICS US, INC. (US) 2023-07-20 WO claimed
EP-4178569-A1 METHOD OF TREATMENT FOR PSILOCYBIN OR PSILOCIN INFUSION Eleusis Therapeutics US, Inc. (US) 2023-05-17 EP claimed
WO-2022082058-A1 METHOD OF TREATMENT BY TRYPTAMINE ALKALOIDS ELEUSIS THERAPEUTICS US, INC. (US) 2022-04-21 WO claimed
WO-2022011350-A1 METHOD OF TREATMENT FOR PSILOCYBIN OR PSILOCIN INFUSION ELEUSIS THERAPEUTICS US, INC. (US) 2022-01-13 WO claimed
US-11154537-B2 Method of treatment for ketamine infusion ELEUSIS THERAPEUTICS US, INC. (US) 2021-10-26 US claimed
US-20210322384-A1 Method of Treatment for Ketamine Infusion ELEUSIS THERAPEUTICS US, INC. (US) 2021-10-21 US claimed
EP-2186515-A1 PHARMACEUTICAL COMPOSITION COMPRISING THE COMBINATION OF AN ANTI-DEPRESSIVE AGENT AND AN ANSIOLYTIC AGENT FOR CONTROL AND TREATMENT OF DEPRESSIVE DISORDERS World Trade Import-Export, WTIE A.G. (CH) 2010-05-19 EP claimed
EP-2168584-A1 PHARMACEUTICAL COMPOSITION COMPRISING THE COMBINATION OF A TRIAZOLOBENZODIAZEPINE AND A SELECTIVE SEROTONIN REUPTAKE INHIBITOR World Trade Import-Export, WTIE A.G. (CH) 2010-03-31 EP claimed
US-6572848-B1 For example taurine, gamma-aminobutyric acid (GABA), isoguvacin, isonipecotic acid, 4,5,6,7-tetrahydroisoxazolo-(5,4-c)pyrid- 3(2H)-one, a benzodiazepine, steroids, and cromakalim, pinacidil, SOCIETE L'OREAL S.A. (FR) 2003-06-03 US claimed
US-6277846-B1 ADMINISTERING TO MAMMAL AN ANTIHISTAMINE-FREE ANTIALLERGENIC AGENT WITH SIDE EFFECT REDUCTION ALLERGAN SALES, INC. 2001-08-21 US claimed
EP-0532512-B1 USE OF PLATELET ACTIVATING FACTOR ANTAGONISTS AS ANTI-PRURITIC AGENTS ALLERGAN INC (US) 1996-12-11 EP claimed
EP-0532512-A4 USE OF PLATELET ACTIVATING FACTOR ANTAGONISTS AS ANTI-PRURITIC AGENTS 1993-05-05 EP claimed
EP-0532512-A1 USE OF PLATELET ACTIVATING FACTOR ANTAGONISTS AS ANTI-PRURITIC AGENTS. ALLERGAN INC (US) 1993-03-24 EP claimed
WO-1991018608-A1 USE OF PLATELET ACTIVATING FACTOR ANTAGONISTS AS ANTI-PRURITIC AGENTS ALLERGAN, INC. (US) 1991-12-12 WO claimed
EP-0127417-B1 PROCESS FOR PREPARING 1-DIMETHYLAMINOMETHYL-TRIAZOLOBENZODIAZEPINES THE UPJOHN COMPANY (US) 1987-05-13 EP claimed
US-4110337-A ANALGESIC, ANTIINFLAMMATORY LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1978-08-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11154537-B2 Method of treatment for ketamine infusion KCND2, KCND3, KCNH3 LMNA 967/4885CCR1 3000/4885CCR5 2243/4885
US-20250073207-A1 PSILOCIN BENZOATE FORMULATION FOR INTRAVENOUS INFUSION SRI, PROC, PRDX6 LMNA 1259/4885CCR1 4471/4885CCR5 3200/4885
US-20210322384-A1 Method of Treatment for Ketamine Infusion KCND2, KCND3, KCNH3 LMNA 967/4885CCR1 3000/4885CCR5 2243/4885
US-20230277568-A1 METHOD OF TREATMENT FOR PSILOCYBIN OR PSILOCIN INFUSION PNN, HTR1B, GABBR1 LMNA 506/4885CCR1 1939/4885CCR5 1259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.