SCHEMBL194481

SCHEMBL194481

c1cnnc2c(c1)ccc1ncnc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.43
CCR1 P32246 3/20 0.43
CCR5 P51681 3/20 0.43
CCR8 P51685 3/20 0.43
CYP3A4 P08684 2/20 0.43
MMP2 P08253 2/20 0.43
TSHR P16473 2/20 0.43
KDM4E B2RXH2 1/20 0.43
GMNN O75496 1/20 0.43
TP53 P04637 1/20 0.43
HSP90AA1 P07900 1/20 0.43
CYP2D6 P10635 1/20 0.43
MAPT P10636 1/20 0.43
MMP9 P14780 1/20 0.43
ALOX15 P16050 1/20 0.43
NFKB1 P19838 1/20 0.43
MMP8 P22894 1/20 0.43
THPO P40225 1/20 0.43
MTOR P42345 1/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10627854 0.87 LMNA (0.34) LMNACCR1CCR5CCR8CYP3A4
Propionic Acid SCHEMBL28455719 0.87 ALDH1A1 (0.37) LMNACCR1CCR5CCR8CYP3A4
Phthalimide SCHEMBL8558624 0.84 GSK3B (0.40) LMNACCR1CCR5CCR8CYP3A4
SCHEMBL11497898 0.79 MAP4K4 (0.33) LMNACCR1CCR5CCR8CYP3A4
SCHEMBL1980670 0.77 LMNA (0.58) LMNACCR1CCR5CCR8CYP3A4
SCHEMBL528130 0.76 LMNA (0.40) LMNACCR1CCR5CCR8CYP3A4
SCHEMBL8669721 0.76 KDM4E (0.40) LMNACYP3A4KDM4EHSP90AA1MAPT
SCHEMBL21001801 0.74 LMNA (0.61) LMNACCR1CCR5CCR8CYP3A4
SCHEMBL157930 0.74 LMNA (0.61) LMNACCR1CCR5CCR8CYP3A4
SCHEMBL31143538 0.73 LMNA (0.59) LMNACCR1CCR5CCR8CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 464 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250073207-A1 PSILOCIN BENZOATE FORMULATION FOR INTRAVENOUS INFUSION ELEUSIS THERAPEUTICS US, INC. 2025-03-06 US claimed
EP-4463153-A1 PSILOCIN BENZOATE FORMULATION FOR INTRAVENOUS INFUSION Eleusis Therapeutics US, Inc. (US) 2024-11-20 EP claimed
US-20230277568-A1 METHOD OF TREATMENT FOR PSILOCYBIN OR PSILOCIN INFUSION ELEUSIS THERAPEUTICS US, INC. 2023-09-07 US claimed
WO-2023137094-A1 PSILOCIN BENZOATE FORMULATION FOR INTRAVENOUS INFUSION ELEUSIS THERAPEUTICS US, INC. (US) 2023-07-20 WO claimed
CN-116143678-A Conjugate linker, cell-binding molecule-drug conjugate containing the same, and preparation and application thereof 杭州多禧生物科技有限公司 2023-05-23 CN claimed
EP-4178569-A1 METHOD OF TREATMENT FOR PSILOCYBIN OR PSILOCIN INFUSION Eleusis Therapeutics US, Inc. (US) 2023-05-17 EP claimed
WO-2022082058-A1 METHOD OF TREATMENT BY TRYPTAMINE ALKALOIDS ELEUSIS THERAPEUTICS US, INC. (US) 2022-04-21 WO claimed
CN-114040779-A Conjugates of cell binding molecules containing branched linkers and cytotoxic agents 杭州多禧生物科技有限公司 2022-02-11 CN claimed
WO-2022011350-A1 METHOD OF TREATMENT FOR PSILOCYBIN OR PSILOCIN INFUSION ELEUSIS THERAPEUTICS US, INC. (US) 2022-01-13 WO claimed
US-11154537-B2 Method of treatment for ketamine infusion ELEUSIS THERAPEUTICS US, INC. (US) 2021-10-26 US claimed
EP-0395527-B1 Imidazobenzodiazepines and their salts, process for preparation, use as medicaments, and compositions containing these compounds ROUSSEL UCLAF (FR) 1994-09-14 EP claimed
EP-0305298-B1 IMIDAZOBENZODIAZEPINES AND THEIR ACID ADDITION SALTS, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1993-09-22 EP claimed
EP-0433163-A2 Process for the preparation of imidazobenzodiazepines and their salts ROUSSEL-UCLAF (FR) 1991-06-19 EP claimed
EP-0423032-A2 Process for the preparation of isoxazolyl and isothiazolyl imidazobenzodiazepines, new derivatives thus obtained, their use as medicaments and compositions containing them ROUSSEL-UCLAF (FR) 1991-04-17 EP claimed
EP-0395527-A1 Imidazobenzodiazepines and their salts, process for preparation, use as medicaments, and compositions containing these compounds ROUSSEL-UCLAF (FR) 1990-10-31 EP claimed
EP-0305298-A2 Imidazobenzodiazepines and their acid addition salts, process and intermediates for their preparation, their use as medicaments and compositions containing them ROUSSEL-UCLAF (FR) 1989-03-01 EP claimed
US-4670433-A CARDIOVASCULAR DISORDERS A/S FERROSAN (DK) 1987-06-02 US claimed
EP-0100906-B1 TRI- AND TETRACYCLIC IMIDAZO(1,5-A)(1,4)BENZODIAZEPIN-1-CARBOXYLIC-ACID DERIVATIVES F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1987-05-13 EP claimed
EP-0197282-A1 Novel oxadiazolyl imidazobenzodiazepine derivatives and methods of preparing such compounds A/S FERROSAN (DK) 1986-10-15 EP claimed
EP-0100906-A2 Tri- and tetracyclic imidazo(1,5-a)(1,4)benzodiazepin-1-carboxylic-acid derivatives F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1984-02-22 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11154537-B2 Method of treatment for ketamine infusion KCND2, KCND3, KCNH3 LMNA 967/4885CCR1 3000/4885CCR5 2243/4885
US-20250073207-A1 PSILOCIN BENZOATE FORMULATION FOR INTRAVENOUS INFUSION SRI, PROC, PRDX6 LMNA 1259/4885CCR1 4471/4885CCR5 3200/4885
US-20230277568-A1 METHOD OF TREATMENT FOR PSILOCYBIN OR PSILOCIN INFUSION PNN, HTR1B, GABBR1 LMNA 506/4885CCR1 1939/4885CCR5 1259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.