Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10595556 | 0.80 | MAOB (0.59) | CYP2A6MAOAMAOBCES1KDM4E | |
| Trimethylammonium SCHEMBL27680388 | 0.80 | CYP2A6 (0.63) | CYP2A6MAOAMAOBCES1KDM4E | |
| Trimethylammonium SCHEMBL2124628 | 0.78 | CYP2A6 (0.61) | CYP2A6MAOAMAOBCES1KDM4E | |
| Benzene SCHEMBL28357254 | 0.78 | MAOB (0.71) | CYP2A6MAOAMAOBCES1KDM4E | |
| SCHEMBL1268680 | 0.76 | MAOA (0.74) | CYP2A6MAOAMAOBCES1L3MBTL1 | |
| SCHEMBL29353311 | 0.76 | MAOA (0.74) | CYP2A6MAOAMAOBCES1L3MBTL1 | |
| SCHEMBL24746 | 0.76 | MAOA (0.74) | CYP2A6MAOAMAOBCES1L3MBTL1 | |
| SCHEMBL5281332 | 0.75 | SMN1; SMN2 (0.49) | CYP2A6MAOAMAOBCES1KDM4E | |
| Propionic Acid SCHEMBL7672868 | 0.74 | MAOA (0.72) | CYP2A6MAOAMAOBCES1KDM4E | |
| Methylamine SCHEMBL27578982 | 0.74 | MAOA (0.65) | CYP2A6MAOAMAOBCES1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1851188-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF ENANTIOMERIC INDANYLAMINE DERIVATIVES | Teva Pharmaceutical Industries Limited (IL) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006120577-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF ENANTIOMERIC INDANYLAMINE DERIVATIVES | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2006-11-16 | — | — | WO | disclosed |