Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27581570 | 0.79 | CYP2A6 (0.45) | SMN1; SMN2NPC1RAB9ATP53MAPT | |
| Acetic Acid SCHEMBL10595556 | 0.79 | MAOB (0.59) | SMN1; SMN2NPC1RAB9AMAPTHPGD | |
| Benzene SCHEMBL28357254 | 0.77 | MAOB (0.71) | HPGDCYP2A6MAOAMAOBCES1 | |
| Ethyl Acetate SCHEMBL28458837 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTHPGDGLACYP2A6 | |
| SCHEMBL1268680 | 0.75 | MAOA (0.74) | CYP2A6MAOAMAOBCES1TDP1 | |
| SCHEMBL29353311 | 0.75 | MAOA (0.74) | CYP2A6MAOAMAOBCES1TDP1 | |
| SCHEMBL24746 | 0.75 | MAOA (0.74) | CYP2A6MAOAMAOBCES1TDP1 | |
| SCHEMBL5281323 | 0.75 | CYP2A6 (0.46) | SMN1; SMN2CYP2A6MAOAMAOBMTNR1A | |
| Toluene SCHEMBL28236425 | 0.73 | LMNA (0.52) | SMN1; SMN2NPC1RAB9AHPGDHTT | |
| Propionic Acid SCHEMBL7672868 | 0.73 | MAOA (0.72) | SMN1; SMN2MAPTHPGDCYP2A6MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1851188-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF ENANTIOMERIC INDANYLAMINE DERIVATIVES | Teva Pharmaceutical Industries Limited (IL) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006120577-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF ENANTIOMERIC INDANYLAMINE DERIVATIVES | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2006-11-16 | — | — | WO | disclosed |