Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 3/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324629 | 0.83 | STING1 (0.37) | PTH1RALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL5321802 | 0.80 | CES2 (0.41) | ALDH1A1GAAHPGDHSD17B10PDE4A | |
| SCHEMBL5324581 | 0.80 | CES2 (0.41) | ALDH1A1GAAHPGDHSD17B10PDE4A | |
| SCHEMBL5320501 | 0.80 | CES2 (0.41) | ALDH1A1GAAHPGDHSD17B10PDE4A | |
| SCHEMBL5324527 | 0.80 | CES2 (0.41) | ALDH1A1GAAHPGDHSD17B10PDE4A | |
| SCHEMBL5325094 | 0.80 | CES2 (0.41) | ALDH1A1GAAHPGDHSD17B10PDE4A | |
| SCHEMBL5322937 | 0.80 | MBTD1 (0.40) | PTH1RALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL5287497 | 0.79 | PTH1R (0.50) | PTH1RALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL5293098 | 0.78 | PTPN1 (0.37) | PTH1RALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL5321770 | 0.77 | LMNA (0.36) | PTH1RALDH1A1GAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129120-A9 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006129120-A2 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2006-12-07 | — | — | WO | disclosed |