Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1L | O00429 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5279488 | 0.81 | ALDH1A1 (0.57) | HPGDALDH1A1TDP1SMN1; SMN2MEN1 | |
| SCHEMBL30730320 | 0.80 | ALDH1A1 (0.58) | HPGDALDH1A1TDP1SMN1; SMN2MEN1 | |
| SCHEMBL5284550 | 0.77 | HSD17B10 (0.50) | DNM1LHPGDALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL5286439 | 0.76 | SMN1; SMN2 (0.48) | HPGDALDH1A1TDP1SMN1; SMN2MEN1 | |
| SCHEMBL5285087 | 0.72 | ALDH1A1 (0.57) | HPGDALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL15356486 | 0.71 | DRD2 (0.42) | DNM1LALDH1A1DRD2HTR2AAOC3 | |
| SCHEMBL25383120 | 0.70 | MEN1 (0.50) | HPGDALDH1A1TDP1SMN1; SMN2MEN1 | |
| SCHEMBL27824215 | 0.70 | HSD17B10 (0.54) | DNM1LHPGDALDH1A1SMN1; SMN2AOC3 | |
| SCHEMBL11912169 | 0.68 | PIM1 (0.44) | DNM1LALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15356505 | 0.68 | DRD2 (0.45) | DNM1LALDH1A1SMN1; SMN2DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | DNM1L 124/4885HPGD 1825/4885ALDH1A1 2972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.