Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5283739 | 0.85 | RAPGEF4 (0.33) | CHKAADRA2AADRA2BADRA2C | |
| SCHEMBL10345008 | 0.85 | ADRA2A (0.38) | TSHRCHKAADRA2AADRA2BADRA2C | |
| SCHEMBL28096130 | 0.80 | P2RX1 (0.38) | TACR1 | |
| SCHEMBL6721319 | 0.78 | TAAR1 (0.51) | MAPTALDH1A1CYP3A4TAAR1 | |
| SCHEMBL12776490 | 0.76 | MAPT (0.39) | TSHRCHKAMAPTALDH1A1TP53 | |
| SCHEMBL157897 | 0.75 | ADRA2A (0.48) | CHKAADRA2AADRA2BADRA2CALDH1A1 | |
| Hydrochloric Acid SCHEMBL27326615 | 0.73 | ADRA2A (0.47) | CHKAADRA2AADRA2BADRA2CALDH1A1 | |
| Trimethylammonium SCHEMBL6555899 | 0.73 | ADRA2A (0.47) | CHKAADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL1042705 | 0.73 | TSHR (0.50) | TSHRCHKAMAPTALDH1A1TP53 | |
| SCHEMBL28233363 | 0.72 | IGLV6-57 (0.37) | TSHRADRA2AADRA2BADRA2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7291926-A | — | — | None | — | — | JP | disclosed |
| WO-2006103342-A9 | INDANYL-PIPERAZINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2007-10-25 | — | — | WO | disclosed |
| WO-2006103342-A2 | INDANYL-PIPERAZINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2006-10-05 | — | — | WO | disclosed |
| JP-H07291926-A | 4-ETHYL-3-PYRROLIN-2-ONE DERIVATIVE AND HERBICIDE CONTAINING THE DERIVATIVE | MITSUI TOATSU CHEM INC | 1995-11-07 | — | — | JP | disclosed |