Trimethylammonium

Trimethylammonium

SCHEMBL6555899

CCN(C)c1ccc(Cl)cc1.CN(C)C

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 2/20 0.47
ADRA2B P18089 2/20 0.47
ADRA2C P18825 2/20 0.47
CNR2 P34972 3/20 0.42
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CYP3A4 P08684 1/20 0.41
CHKA P35790 4/20 0.39
LMNA P02545 1/20 0.38
CYP2A6 P11509 1/20 0.38
AOC3 Q16853 1/20 0.38
POLB P06746 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CNR1 P21554 1/20 0.37
CHRM1 P11229 1/20 0.36
HTR2A P28223 1/20 0.36
MCHR1 Q99705 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL157897 0.98 ADRA2A (0.48) ADRA2AADRA2BADRA2CCNR2ALDH1A1
Hydrochloric Acid SCHEMBL27326615 0.95 ADRA2A (0.47) ADRA2AADRA2BADRA2CCNR2ALDH1A1
SCHEMBL10330355 0.84 ADRA2A (0.58) ADRA2AADRA2BADRA2CALDH1A1KDM4E
Trimethylammonium SCHEMBL6555079 0.81 CNR2 (0.59) CNR2ALDH1A1KDM4ECYP3A4TDP1
SCHEMBL6859648 0.79 CHRM1 (0.42) ALDH1A1KDM4EHPGDALOX15HSD17B10
SCHEMBL10888104 0.79 MEN1 (0.41) CNR2LMNACHRM1HTR2AMCHR1
SCHEMBL6553827 0.78 CNR2 (0.51) ADRA2ACNR2ALDH1A1KDM4ECNR1
SCHEMBL762882 0.77 ALDH1A1 (0.61) ADRA2AADRA2BADRA2CALDH1A1KDM4E
SCHEMBL4400993 0.77 ADRA2A (0.52) ADRA2AADRA2BADRA2CALDH1A1KDM4E
SCHEMBL18323114 0.77 ADRA2A (0.52) ADRA2AADRA2BADRA2CALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1234007-B1 OLIGOMERIC METHINE DYES CLARIANT FINANCE BVI LTD (VG) 2004-02-18 EP disclosed
EP-1234007-A1 OLIGOMERIC METHINE DYES Clariant Finance (BVI) Limited (VG) 2002-08-28 EP disclosed
WO-2001036543-A1 OLIGOMERIC METHINE DYES CLARIANT FINANCE (BVI) LIMITED (VG) 2001-05-25 WO disclosed