SCHEMBL5281767

SCHEMBL5281767

Cn1nnc(C#N)c1C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 1/20 0.38
LMNA P02545 1/20 0.35
KMT2A Q03164 1/20 0.35
CTSS P25774 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5282665 0.85 CYP11B2 (0.30) CYP11B2
SCHEMBL5279855 0.83
SCHEMBL5280125 0.80
SCHEMBL5276236 0.77
SCHEMBL5277432 0.77 CTSK (0.33) CYP11B2
SCHEMBL5275898 0.76
SCHEMBL5273941 0.74 SLC9A1 (0.36) CYP11B2
SCHEMBL5277467 0.72
SCHEMBL5282197 0.72 SLC9A1 (0.39)
SCHEMBL14996593 0.71 CYP11B2 (0.37) CYP11B2LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859781-A2 Brightening and/or colouring agent with triazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed