Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2342911 | 0.78 | ALDH1A1 (0.50) | NPSR1ALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL4607473 | 0.78 | ALDH1A1 (0.50) | NPSR1ALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL4607464 | 0.78 | ALDH1A1 (0.50) | NPSR1ALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL11141654 | 0.78 | LMNA (0.46) | NPSR1ALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL2543696 | 0.77 | ALDH1A1 (0.63) | NPSR1ALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL13603789 | 0.76 | NPSR1 (0.48) | NPSR1ALDH1A1LMNASMN1; SMN2RAB9A | |
| SCHEMBL7621077 | 0.76 | TDP1 (0.43) | NPSR1ALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL13519347 | 0.76 | ALDH1A1 (0.52) | NPSR1ALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL18491075 | 0.74 | ALDH1A1 (0.42) | NPSR1ALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL11178102 | 0.73 | NPSR1 (0.44) | NPSR1ALDH1A1LMNASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866416-A2 | DELIVERY SYSTEMS AND METHODS FOR DIAGNOSING AND TREATING CARDIOVASCULAR DISEASES | Medstar Health Inc. (US) | 2007-12-19 | — | — | EP | claimed |
| WO-2006102395-A2 | DELIVERY SYSTEMS AND METHODS FOR DIAGNOSING AND TREATING CARDIOVASCULAR DISEASES | MEDSTAR HEALTH INC (US) | 2006-09-28 | — | — | WO | claimed |
| US-11059886-B1 | Methods and compositions for treating inflammatory or autoimmune diseases or conditions using GRM8 activators | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2021-07-13 | — | — | US | disclosed |
| EP-2580215-A2 | 8-(2'-HETEROCYCYL)PYRIDO[2.3-D]PYRIMIDIN-7(8H)-ONES FOR THE TREATMENT OF CNS DISORDERS | Afraxis, Inc. (US) | 2013-04-17 | — | — | EP | disclosed |
| WO-2011156775-A2 | 8-(2'-HETEROCYCYL)PYRIDO[2.3-D]PYRIMIDIN-7(8H)-ONES FOR THE TREATMENT OF CNS DISORDERS | AFRAXIS, INC. (US) | 2011-12-15 | — | — | WO | disclosed |